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Moumoujus

OLIGOPEPTIDE-8.

Insufficient Data CAS - / ANTIMICROBIAL

OLIGOPEPTIDE-8 is a sophisticated signaling peptide designed to encourage the skin's inherent renewal processes, promoting the synthesis of essential proteins like collagen and elastin. Beyond its general anti-aging potential, it uniquely contributes antimicrobial properties to help manage skin microbiota.

Summary

Skin conditioning agent Anti-aging agent Antimicrobial agent Hydrator Anti-inflammatory Antioxidant

Science

Mechanism of Action

OLIGOPEPTIDE-8 operates by signaling skin cells to activate their endogenous repair mechanisms. This molecular communication stimulates the enhanced production of structural proteins, specifically collagen and elastin, which are crucial for maintaining skin integrity, firmness, and elasticity, thereby reducing the appearance of fine lines and wrinkles while improving overall plumpness. It also supports increased cellular resilience against damaging factors, aids in normalizing metabolic pathways, and optimizes tissue regeneration. Notably, OLIGOPEPTIDE-8 possesses distinct antimicrobial capabilities, assisting in the inhibition of microbial proliferation on the skin's surface.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

As a water-soluble peptide, OLIGOPEPTIDE-8 is best incorporated into water-rich emulsion systems, which are suggested to enhance its hydrophilic penetration through the lipophilic stratum corneum. While specific optimal pH ranges for OLIGOPEPTIDE-8 are not detailed, the stability of peptides in general is pH-dependent; careful formulation pH selection is vital, particularly as sulfur-containing amino acids within peptides are prone to oxidation and oligomerization.

Synergies

  • Retinol

Conflicts

  • Microbial contamination
  • Oxidizing agents

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR), SCCS, or FDA have not provided specific safety assessments for OLIGOPEPTIDE-8, rendering its official status as 'insufficient data'. Although a distinct peptide, Acetyl Hexapeptide-8 Amide, has a CIR assessment deeming it safe at concentrations up to 0.005%, this does not directly apply. Approval of Oligopeptides #1-23 by the Russian Ministry of Health exists, but this is not equivalent to international regulatory body consensus.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

While OLIGOPEPTIDE-8 offers promising general benefits of peptides like skin repair and antimicrobial action, its specific clinical efficacy and safety profile require further dedicated research.

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