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Moumoujus

OLIGOPEPTIDE-28.

Insufficient Data CAS - / ANTIOXIDANT, BINDING, CHELATING, SKIN PROTECTING

Oligopeptide-28 is a synthetic peptide engineered to support the skin's natural repair mechanisms. Functioning as an antioxidant and skin-protecting agent, it aims to regenerate mature skin and enhance structural integrity, contributing to a reduction in the visible signs of aging.

Summary

Antioxidant Skin Protecting Binding Chelating Skin Regeneration Stimulates Collagen Production Stimulates Elastin Production Reduces Wrinkles Improves Skin Elasticity Moisturizing Properties Promotes Skin Cell Regeneration Strengthens Hair Roots Promotes Hair Growth Protects Against Environmental Damage Reduces Irritation Fights Inflammation Strengthens Skin Barrier

Science

Mechanism of Action

This synthetic oligopeptide acts by signaling the body to activate its inherent skin repair mechanisms, promoting the regeneration of mature skin, strengthening its underlying structure, and contributing to a visible reduction in wrinkles. Oligopeptide-28 also functions as an antioxidant, inhibiting oxidative processes, and acts as a binding and chelating agent. More broadly, oligopeptides are known to stimulate collagen and elastin production, improve skin elasticity, and promote cellular regeneration.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

No information regarding 'dusting' or typically low effective concentrations was found in the provided research data for Oligopeptide-28.

The Formula

Formulation

Solubility
Unknown
Optimal pH N/A
0 7 14

Stability

Specific stability data for Oligopeptide-28 is currently unavailable. However, peptides generally are susceptible to degradation, necessitating careful formulation. Optimal pH ranges for related oligopeptides have been observed between pH 3-7 (e.g., Oligopeptide-20: pH 3-6; Oligopeptide-10: pH 5-7). Peptides containing sulfur amino acids are particularly prone to oxidation and oligomerization. For enhanced stability, storage at low temperatures (e.g., -20 °C) is commonly recommended. When formulating, late-stage incorporation below 45 °C (e.g., for Oligopeptide-10) or 35-40 °C (e.g., for Oligopeptide-20) is often advised.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

A specific safety assessment by the Cosmetic Ingredient Review (CIR) for Oligopeptide-28 is not available, with the CIR indicating a need for specific peptide sequence evaluation for adequate assessment. The SCCS has not published an opinion. The FDA regulates peptides as drugs for therapeutic uses, and there is no specific FDA status for Oligopeptide-28 as a cosmetic ingredient. COSMILE Europe indicates no GHS hazard classification found, and oral, dermal, and inhalation toxicity for Oligopeptide-28 are 'not determined'. While a related peptide (Oligopeptide-20) showed no irritation in a patch test, direct safety validation for Oligopeptide-28 is limited.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

Oligopeptide-28 exhibits promising potential as an antioxidant and regenerative agent, leveraging general oligopeptide benefits. However, a conclusive assessment is pending due to the current lack of specific clinical efficacy and comprehensive safety data directly for Oligopeptide-28.

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