Science
Mechanism of Action
This biomimetic peptide primarily functions by up-regulating the expression of Epidermal Growth Factor (EGF), a crucial factor for skin cell proliferation and renewal. It imitates key elements involved in the natural regeneration of epidermal and dermal structures, including hyaluronic acid, collagen, elastin, and fibronectin. Oligopeptide-24 stimulates fibroblast activity, thereby promoting the synthesis and secretion of elastin and hyaluronic acid. Additionally, it contributes to cell growth, migration, and survival, fostering the production of extracellular matrix components and specific growth factors within skin cell lines, while also mitigating inflammatory responses.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 In vitro research indicates Oligopeptide-24 significantly increases Epidermal Growth Factor (EGF) concentration in fibroblast cells within 72 hours under serum-free culture conditions.
- 02 Laboratory studies demonstrate a threefold enhancement in hyaluronic acid expression and a 1.3 times increase in elastin expression in fibroblast cells, showing a dose-dependent response.
- 03 It has been shown to elevate endogenous growth factor concentrations in skin up to tenfold compared to controls in in vitro settings.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
This peptide exhibits excellent stability, effectively maintaining its efficacy even when exposed to high temperatures and bright light.
Safety
Safety Profile
Laboratory studies consistently demonstrate minimal cytotoxicity for Oligopeptide-24 at typical research concentrations. No significant irritation, sensitization, or phototoxic reactions have been observed in various in vitro or ex vivo skin models, affirming its non-allergenic and non-irritating profile.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Oligopeptide-24 is a valuable biomimetic peptide that powerfully supports skin regeneration, hydration, and elasticity, while also offering anti-inflammatory benefits, making it suitable for all skin types.
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