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OLIGOPEPTIDE-21.

Insufficient Data CAS - / SKIN CONDITIONING

Oligopeptide-21 is a synthetic signaling peptide engineered to diminish the appearance of lines and deep wrinkles. It actively promotes collagen and elastin synthesis, thereby enhancing skin elasticity and contributing to cellular rejuvenation.

Anti-aging Reduces fine lines and wrinkles Boosts collagen production Boosts elastin production Improves skin elasticity Promotes skin cell regeneration Skin brightening

Science

This synthetic peptide operates by emulating natural skin rejuvenation proteins, essential for growth, healing, and wound repair processes. Its primary action involves stimulating the dermal production of collagen and elastin, critical components for maintaining skin firmness and elasticity, and fostering the generation of new skin cells to reduce and prevent visible signs of aging.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

Specific data on dusting for Oligopeptide-21 is not available. However, peptides are generally active at low concentrations, making them less prone to being used solely for 'dusting' at ineffective levels, especially when compared to bulk ingredients.


The Formula

Solubility
Water
Optimal pH 3 – 6
0 7 14

Stability

For optimal stability, related peptides like Oligopeptide-20 are typically incorporated into formulations during the final stages, at temperatures between 35-40 °C. Maintaining a careful pH within the 3-6 range (optimal for Oligopeptide-20) is crucial for peptide integrity. Peptides containing sulfur amino acids, such as methionine and cysteine, are susceptible to oxidation and oligomerization, respectively; formulating under inert atmospheres and including reducing agents can mitigate these degradation pathways.


Safety

CIR Status
Not reviewed
Sensitization risk Low

Specific safety assessments by regulatory bodies such as CIR, SCCS, or FDA for Oligopeptide-21 are currently unavailable. Nevertheless, peptides are broadly regarded as safe and well-tolerated across various skin types in cosmetic applications. A related peptide, Oligopeptide-20, demonstrated non-irritant properties in a 48-hour patch test.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Insufficient Data

Oligopeptide-21 presents a compelling mechanism for anti-aging and skin rejuvenation, supported by promising clinical data from a related peptide, but direct efficacy studies on Oligopeptide-21 itself are currently limited.


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