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Moumoujus

OLIGOPEPTIDE-20.

Valuable CAS - / SKIN CONDITIONING

Oligopeptide-20 is a precision-engineered 12-amino acid synthetic peptide designed to rejuvenate the skin by mimicking natural growth factors. It actively supports cell renewal and enhances the skin's structural integrity, visibly reducing signs of aging while promoting overall skin health.

Summary

Skin conditioning Anti-aging Skin regeneration Collagen boosting Hyaluronic acid boosting Elastin production Skin barrier strengthening Firming Even skin tone

Science

Mechanism of Action

This synthetic peptide functions as a positive regulator of cell proliferation, emulating Somatomedin, a crucial growth factor for skin repair and regeneration. It significantly boosts the proliferation of skin keratinocytes and fibroblasts, accelerating the restoration of damaged skin. Furthermore, Oligopeptide-20 elevates the production of essential extracellular matrix components such as collagen, elastin, and hyaluronic acid, simultaneously strengthening the skin barrier and microvessel walls. It also acts as a tissue inhibitor of metalloproteinases (TIMP-2), which helps maintain extracellular matrix integrity, leading to improved elasticity, firmness, and a more uniform skin tone.

Research

Clinical Evidence

Medium confidence
Effective range 0.003–0.003%
Optimal

0.003%

Transparency

Dusting Analysis

Commonly dusted
Min. effective
0.003%
Red flag below
0.0015%

As a highly potent peptide, Oligopeptide-20 demonstrates significant efficacy at a very low concentration of 0.003% w/w. Formulations containing less than this clinically proven threshold, particularly at or below 0.0015% w/w, may not deliver the observed anti-aging and skin renewal benefits, potentially indicating a 'dusting' scenario.

The Formula

Formulation

Solubility
Water
Optimal pH 3 – 6
0 7 14

Stability

For maximum stability, store Oligopeptide-20 sealed and protected from light at 2-8°C, with long-term storage recommended at -15 to -20°C. When formulating, integrate the peptide at the final stage of product development, ensuring the temperature is between 35-40°C.

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
0.005%
Sensitization risk Low

Extensive testing, including a 48-hour semi-occluded patch test, confirms Oligopeptide-20 is non-irritating and does not compromise the skin barrier. It is also reported to be free of heavy metals and safe for both skin and eye contact, with a maximum recommended cosmetic concentration of 0.005% w/w (50 ppm).

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Oligopeptide-20 is a valuable peptide for anti-aging and skin health, effectively improving wrinkle appearance and roughness, and bolstering skin's natural regeneration processes across all skin types.

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