Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle
Moumoujus

OLIGOPEPTIDE-178.

Valuable / NOT REPORTED

Oligopeptide-178 is an innovative, biotechnologically produced peptide derived from engineered spider silk protein. It forms a protective, breathable film on the skin, enhancing its appearance and texture while offering an instant firming sensation. This versatile ingredient contributes to a healthier skin barrier and a refined, soft feel.

Summary

Film-forming Skin conditioning Skin protecting Non-surfactant dispersant Emollient

Science

Mechanism of Action

This single-chain recombinant polypeptide, generated through fermentation of gene-modified yeast, mimics a crucial segment of natural spider silk protein. Its primary action involves creating a protective film that shields both skin and hair from environmental aggressors, including pollution, UV radiation, and blue light. Beyond protection, Oligopeptide-178 acts as an emollient, imparting a desirable silky sensory profile superior to many conventional silicone-based ingredients, ultimately promoting a healthy skin appearance.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Incorporation into skincare formulations leads to a healthy skin appearance, a silky-soft texture, and an instant firming effect.

Transparency

Dusting Analysis

Not commonly dusted

No specific data suggests Oligopeptide-178 is commonly 'dusted' or used at ineffective concentrations for marketing purposes. Its reported benefits are associated with its functional presence in formulations.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Oligopeptide-178 is described as a stable, powerful biotechnological peptide. It is biodegradable, skin microflora-friendly, and exists as a hydrophilic powder, simplifying its integration into water-based formulations.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Formal safety assessments by CIR, SCCS, or FDA are not yet available for Oligopeptide-178. However, independent analyses provide reassuring indications: EWG Skin Deep rates it 'LOW' for cancer, allergies, immunotoxicity, and respiratory irritation, albeit with 'Low Availability' of scientific studies. SkinSAFE extensively identifies it as 'Teen SAFE', 'Lip SAFE', 'Baby SAFE', and 'Eyelid SAFE', confirming it is free of common allergens and irritants. Paula's Choice indicates it is 'Not rated' as their team is still reviewing research.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Oligopeptide-178 is a valuable, innovative peptide offering broad protective, conditioning, and sensory benefits across all skin types, with a favorable safety profile.

Related

Similar Ingredients

Finding similar ingredients…