Science
Mechanism of Action
Oligopeptide-121, a bio-identical vegan collagen signal peptide, is generated through bacterial fermentation. It functions as a cellular messenger, activating fibroblasts to profoundly increase the production of vital skin components such as collagen, elastin, and hyaluronic acid. By bolstering these supportive elements, it enhances the skin's tensile strength, promotes optimal skin cell renewal, and actively strengthens the skin barrier. Its composition includes amino acid triplets, notably Gly-Pro-Hyp (Tripeptide-29), which are crucial for natural collagen synthesis and effectively smooth the appearance of wrinkles.
Research
Clinical Evidence
High confidenceN/A
Key findings
- 01 Demonstrated significant improvement in skin's firm look and feel, alongside effective smoothing of wrinkle appearance and soothing properties that may reduce puffy eyes and reddened skin.
- 02 Positively influences the elasticity and resistance of the skin, exhibiting superior performance over marine collagen in boosting the production of collagen, elastin, and fibronectin.
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
Evaluated as 'safe as used' by CIR for broader peptide and protein categories, with specific reviews for Sh-Polypeptide-121 not individually found. It exhibits excellent skin compatibility, deemed 'Irritant Free' by SkinSAFE and considered safe for sensitive areas like eyelids and lips, as well as for babies and teens. EWG Skin Deep rates its hazard scores as 'LOW' across all categories, including cancer, allergies, immunotoxicity, and developmental/reproductive toxicity.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Oligopeptide-121 is a highly valuable ingredient for advanced skincare, offering comprehensive benefits in firming, wrinkle reduction, and skin rejuvenation with an excellent safety profile.
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