Science
Mechanism of Action
Functioning as a protective and conditioning agent, Oligopeptide-11 is theorized to bolster the skin's natural defenses against environmental stressors. As a member of the broader oligopeptide family, it is generally understood to stimulate the production of vital skin proteins like collagen and elastin, fostering cellular renewal and repair processes. This action contributes to improved skin elasticity and overall radiance, with its small size enabling more effective permeation of the skin barrier to initiate these beneficial cellular activities. Some related oligopeptides also exhibit potential anti-inflammatory and antibacterial properties.
Research
Clinical Evidence
Insufficient-data confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
The stability of oligopeptides is highly sensitive to pH, necessitating careful selection during formulation. For related peptides such as Oligopeptide-1 (EGF), a cream pH between 5 and 8 is often required to prevent decomposition by enzymes and microorganisms. Oligopeptides containing sulfur-bearing amino acids are also susceptible to oxidation and oligomerization, which can impact product integrity.
Conflicts
- strong acids/alkalis
- strong oxidizing/reducing agents
- microbial contamination
Safety
Safety Profile
Specific regulatory information for SH-Oligopeptide-11 from manufacturers is currently not available. While the Cosmetic Ingredient Review (CIR) has conducted safety assessments on broader categories like 'Tissue-Derived Proteins and Peptides,' Oligopeptide-11 itself is not specifically detailed in their provided summaries. The FDA has not listed Oligopeptide-11 among bulk drug substances that may present significant safety risks for compounding.
Your Skin
Skin Compatibility
Our Assessment
Verdict
While Oligopeptide-11 offers theoretical benefits as a protective and conditioning agent based on general oligopeptide mechanisms, specific clinical efficacy and comprehensive safety data for this particular peptide are currently insufficient for a definitive rating.
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