Science
Mechanism of Action
This advanced peptide operates by modulating cellular signaling pathways within the skin, particularly those linked to extracellular matrix components. By influencing fibroblast activity, Oligopeptide-104 facilitates targeted communication, which is crucial for maintaining optimal skin structure and elasticity. It is understood to stimulate collagen production, diminish the visibility of fine lines and wrinkles, and attract moisture to enhance hydration. Furthermore, it contributes to skin's natural repair processes and cell turnover, exhibits antioxidant activity, and may help normalize melanin production to address hyperpigmentation.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 In dental applications, Oligopeptide-104 (P11-4) demonstrated superior remineralization in an in vitro study, restoring enamel surface hardness by 54.1% compared to control materials.
- 02 Clinical trials for dental use indicated that early carious lesions treated with P11-4 experienced significantly reduced size, outperforming fluoride varnish treatments.
Transparency
Dusting Analysis
No data available to assess dusting practices for this ingredient in cosmetic formulations.
The Formula
Formulation
Stability
Oligopeptide-104 is water-soluble due to its hydrophilic molecular structure, facilitating hydrogen bonding with water. Its self-assembly mechanism is pH-dependent, maintaining a monomeric state above pH 7.5 and forming a nematic gel specifically between pH 6.8 and 7.2. Flocculation of the gel has been observed after multiple pH shifts, suggesting that environments with fluctuating pH may impact its long-term stability and aggregation state.
Safety
Safety Profile
Oligopeptide-104 possesses an FDA UNII code (MUM5TLH7X6) and is generally characterized by good biocompatibility with no significant reported toxicity or side effects. However, comprehensive safety assessments by regulatory bodies like CIR or SCCS for cosmetic use are not yet available.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Oligopeptide-104 is a valuable peptide for advanced skincare formulations, offering broad benefits from anti-aging and hydration to skin repair, despite current clinical studies primarily focusing on dental and hair applications rather than direct skin efficacy in specific concentrations.
Related
Similar Ingredients
Finding similar ingredients…