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Moumoujus

OLIGOPEPTIDE-101 AMIDE.

Insufficient Data / ANTI-SEBUM, ANTIMICROBIAL, ANTIOXIDANT, SKIN PROTECTING

Oligopeptide-101 Amide is a multi-functional peptide designed to support overall skin health. It exhibits properties as an antimicrobial, antioxidant, anti-sebum, and skin protecting agent, working to fortify the skin's natural defenses and regenerative capabilities.

Summary

Antimicrobial Antioxidant Sebum Regulator Skin Protectant Collagen Stimulator Elastin Stimulator Moisturizer Anti-inflammatory Barrier Strengthener Regenerative

Science

Mechanism of Action

This ingredient functions by signaling skin cells to initiate endogenous repair pathways, promoting cellular regeneration and strengthening the skin's structural integrity. It actively stimulates the production of collagen and elastin, which are crucial for maintaining skin firmness and elasticity. Additionally, Oligopeptide-101 Amide enhances cellular efficiency for a more vibrant complexion, provides moisturizing benefits, reduces irritation and inflammation, and reinforces the skin's protective barrier.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

Specific data regarding the common dusting practices or critical concentrations for Oligopeptide-101 Amide are not available within the current research.

The Formula

Formulation

Solubility
Water
Optimal pH 5 – 8
0 7 14

Stability

Peptides, including those with amide bonds, are highly sensitive to variations in pH and temperature. Optimal stability for this class of ingredients is typically achieved within a pH range of 5.0 to 8.0, although some related oligopeptides show optimal stability between pH 5-7. Extreme acidic or basic conditions can induce hydrolysis of side-chain amide moieties and aspartimide formation, leading to degradation and impurity generation. For optimal stability, Oligopeptide-101 Amide should be stored at controlled low temperatures, ideally -20°C, to minimize degradation due to residual moisture. Incorporation into formulations should occur during the final manufacturing stage at temperatures below 45°C.

Conflicts

  • Strongly acidic conditions
  • Strongly basic conditions
  • High temperatures

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

No specific safety assessments from regulatory bodies such as CIR, SCCS, or FDA were found for Oligopeptide-101 Amide. However, the CIR Expert Panel has evaluated other amides, deeming some, like Acetyl Hexapeptide-8 Amide, safe at concentrations up to 0.005%, with further data needed for higher levels. Alkoxylated fatty amides were also deemed safe when formulated to be non-irritating.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

Oligopeptide-101 Amide presents a promising array of benefits for skin health; however, specific clinical efficacy and safety data for this precise peptide are currently insufficient for a definitive assessment.

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