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OLEOYL TETRAPEPTIDE-31.

Valuable / ANTIOXIDANT, SKIN CONDITIONING

Oleoyl Tetrapeptide-31 is a dual-action ingredient functioning as both a signaling peptide and an antioxidant. It is engineered to support the skin's natural repair mechanisms, promoting cellular regeneration and safeguarding against oxidative damage.

antioxidant skin conditioning anti-aging

Science

This ingredient operates on two fronts: as a peptide, it consists of specific amino-acid chains that signal the skin to activate its intrinsic repair processes, thereby stimulating the regeneration of mature skin, fortifying its structural integrity, and visibly reducing the appearance of wrinkles. Concurrently, its antioxidant properties allow it to neutralize oxygen-promoted reactions, effectively preventing the oxidation of other cosmetic ingredients and shielding skin cells from detrimental oxidative stress. This dual action contributes to correcting signs of aging, brightening skin tone, and potentially stimulating collagen synthesis.


Research

Medium confidence
Effective range 0.0001–0.003%
Optimal

N/A

Key findings

  1. 01 General peptide research indicates that at concentrations typically ranging from 0.0001% to 0.003% (1-30 ppm), peptides can significantly stimulate the regeneration of mature skin, enhance its structure, and contribute to a visible reduction in wrinkles. This leads to an improved complexion and increased elasticity, mimicking the skin's natural repair processes. Customary use for certain peptides has been noted below 0.001% (10 ppm).

Transparency

Commonly dusted
Min. effective
0.0001%
Red flag below
0.0001%

Given its effective concentration range in parts per million (ppm), Oleoyl Tetrapeptide-31 is particularly susceptible to 'dusting.' Formulations containing it below the clinically indicated minimum effective threshold of 0.0001% (1 ppm) may not deliver its intended benefits, serving more as a label claim than an active treatment.


The Formula

Solubility
Unknown
Optimal pH N/A
0 7 14

Safety

CIR Status
Not reviewed
Sensitization risk Unknown

As of the available research, Oleoyl Tetrapeptide-31 has not undergone specific safety reviews by major regulatory bodies such as the Cosmetic Ingredient Review (CIR), Scientific Committee on Consumer Safety (SCCS), or the FDA. Further comprehensive assessment is needed to establish its full safety profile.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

Oleoyl Tetrapeptide-31 is a valuable ingredient offering significant anti-aging and protective benefits through its peptide signaling and antioxidant actions, though specific clinical validation for this compound and comprehensive safety reviews are still pending.


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