Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle
Moumoujus

OLEOYL SARCOSINE.

Valuable CAS 110-25-8 / ANTISTATIC, CLEANSING, HAIR CONDITIONING, SURFACTANT - CLEANSING

Oleoyl Sarcosine is an anionic N-acylamino acid surfactant that efficiently cleanses skin and hair by facilitating the emulsification of oils and dirt. Beyond its purifying properties, it functions as an effective emulsifier, stabilizing emulsion formulations, and potentially augmenting the penetration of other active ingredients into the skin.

Summary

Surfactant Cleansing agent Wetting agent Hair conditioning agent Emulsifier Antimicrobial agent Virucidal agent Penetration enhancer

Science

Mechanism of Action

This amphiphilic N-acylamino acid acts as an anionic surfactant, reducing surface tension to allow water to effectively mix with lipids and impurities for rinsing. Its unique sarcosine head group interacts with polar surfaces, contributing to refined product texture and an enhanced skin feel. Furthermore, Oleoyl Sarcosine demonstrates antimicrobial and virucidal properties and has been noted to potentially enhance the transdermal delivery of co-formulated ingredients.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Oleoyl Sarcosine exhibits robust chemical stability across a wide pH range, including high alkaline conditions, due to its carboxamide structure. While primarily soluble in oil and various organic solvents, it can be effectively solubilized in water under alkaline pH conditions.

Synergies

  • Enhances the penetration of other active ingredients into the skin

Conflicts

  • Strong oxidizing agents
  • Ingredients known to lead to the formation of N-nitroso compounds

Safety

Safety Profile

CIR Status
Safe with restrictions
Max tested
5%
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) Expert Panel concludes that Oleoyl Sarcosine is safe for use in rinse-off products. For leave-on applications, it is considered safe at concentrations up to 5%, provided the final product is formulated to be non-irritating. A critical safety consideration involves avoiding co-formulation with ingredients that could lead to the formation of N-nitroso compounds, as sarcosine can potentially nitrosate into N-nitrososarcosine, a compound of toxicological concern. While related N-Acyl Sarcosines are FDA-approved for specific food contact uses, and Oleoyl Sarcosine is listed in the FDA's inventory of food contact substances, data concerning safety for inhalation exposure is currently insufficient.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Oleoyl Sarcosine is a valuable multi-functional ingredient, offering effective cleansing, emulsification, potential penetration enhancement, and antimicrobial benefits, provided strict adherence to formulation guidelines is maintained to ensure safety and prevent nitrosamine formation.

Related

Similar Ingredients

Finding similar ingredients…