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OLEIC ACID.

Valuable CAS 112-80-1 / SKIN CONDITIONING - EMOLLIENT, SURFACTANT - EMULSIFYING

A monounsaturated omega-9 fatty acid, Oleic Acid is a potent emollient that deeply hydrates and strengthens the skin's natural lipid barrier. It is recognized for its ability to improve the absorption of other active ingredients, enhancing overall product performance.

Emollient Emulsifying Skin-identical ingredient Penetration Enhancer Hydrating Barrier Support Anti-inflammatory Antioxidant

Science

Oleic Acid functions by penetrating the epidermal layers to deliver profound hydration, effectively locking in moisture and preventing transepidermal water loss. It reinforces the skin's protective lipid barrier, thereby diminishing sensitivity and fostering an optimal environment for moisture retention. Its inherent emollient qualities contribute to a soft, smooth complexion by forming a non-greasy protective film. Beyond hydration, Oleic Acid exhibits anti-inflammatory properties that can soothe redness and discomfort, and it acts as an antioxidant to combat free radical damage, supporting anti-aging efforts by preserving skin elasticity and minimizing the appearance of fine lines. Crucially, it enhances the penetration of other skincare actives by temporarily disrupting the stratum corneum's lipid bilayers and creating microscopic lacunae, improving their bioavailability.


Research

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 In a study, a 10% concentration of Oleic Acid significantly increased epidermal permeability in rat skin over a 2-hour period. This was achieved by perturbing the stratum corneum's lipid bilayers and promoting lacunae formation, thus enhancing transdermal drug delivery.
  2. 02 Preliminary research from 2021 suggests Oleic Acid may contribute to skin brightening by fostering a healthy skin barrier. However, further investigation is required to fully substantiate this specific effect.

Transparency

Not commonly dusted

No specific data regarding 'dusting' behavior for Oleic Acid was identified in the research.


The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Oleic Acid is prone to oxidation upon exposure to air, particularly when impure, which can lead to discoloration (yellowish to brown) and the development of a rancid odor. Its ionization state and aggregation patterns are significantly influenced by pH, with an approximate pKa of 5.02 in aqueous solutions. It reacts with alkalies to form soaps.

Synergies

  • Other active ingredients (due to penetration enhancement)

Conflicts

  • strong oxidizing agents
  • aluminum
  • alkalies

Safety

CIR Status
Safe as used
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has deemed Oleic Acid safe for use in cosmetic products at current practice levels. The FDA also recognizes it as generally safe (GRAS). However, animal studies involving single topical applications at higher concentrations (up to 50%) sometimes elicited responses ranging from no toxicity to erythema, hyperkeratosis, and hyperplasia. Acute intradermal administration up to 25% caused local inflammation and necrosis. While pure Oleic Acid is generally considered non-comedogenic, formulations containing high amounts of oleic acid-rich oils or impurities may potentially exacerbate breakouts in individuals with oily or acne-prone skin. Furthermore, topical application, especially in pure form, might provoke sensitivity, redness, irritation, or rashes in very sensitive skin types.


Your Skin

Yes Normal
Yes Dry
No Oily
No Sensitive
Irritancy Low
Comedogenicity Medium

Our Assessment

Valuable

Oleic Acid is a valuable ingredient for enhancing hydration, strengthening the skin barrier, and boosting the efficacy of other actives, particularly beneficial for dry and normal skin types. However, careful consideration of formulation and individual skin sensitivity is advised for oily or highly sensitive skin.


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