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OENOTHERA BIENNIS EXTRACT.

Valuable CAS 90028-66-3 / ANTIOXIDANT, SKIN CONDITIONING - MISCELLANEOUS, SKIN PROTECTING

Oenothera Biennis Extract, derived from Evening Primrose, is a multifaceted botanical ingredient recognized for its robust skin-conditioning properties. Rich in omega-6 fatty acids and antioxidants, it works to enhance skin hydration, reduce inflammation, and combat visible signs of aging, making it suitable for a range of skin concerns.

Summary

Antioxidant Anti-inflammatory Moisturizing Anti-aging Skin conditioning Barrier support Redness reduction Hyaluronic acid boosting Collagen support

Science

Mechanism of Action

This extract operates by leveraging its high content of omega-6 fatty acids, phenolic compounds, and flavonoids, which collectively provide potent antioxidant and anti-inflammatory benefits. It supports the skin's natural lipid barrier, fostering regeneration and diminishing redness. In vitro research further demonstrates its ability to promote essential extracellular matrix protein production, including matrix collagen contraction and actin polymerization, alongside enhancing moisturization by upregulating hyaluronic acid synthase 2 (HAS2) and aquaporin 3 (AQP3).

Research

Clinical Evidence

Medium confidence
Effective range 5–10%
Optimal

5%

Key findings

  1. 01 A topical use level of 5-10% is recommended for Oenothera Biennis flower extract, specifically when standardized to 20% in a water- and glycerin-blend, due to its antioxidant and anti-inflammatory properties.
  2. 02 In vitro studies using Oenothera biennis cell cultures demonstrated anti-aging activity at concentrations between 0.0004% and 0.05%, promoting matrix collagen contraction, actin polymerization, and the production of essential extracellular matrix proteins without cytotoxicity at 0.01%.
  3. 03 In vitro research on Oenothera biennis sprout extract revealed significant antioxidant capacity, anti-wrinkle activity through the inhibition of matrix metalloproteinases-1 and -2, and enhanced skin hydration via increased hyaluronic acid levels and the expression of moisturizing genes (HAS2, AQP3).

Transparency

Dusting Analysis

Not commonly dusted

The recommended topical use levels for Oenothera Biennis Extract, when supplied as a standardized blend, range from 5% to 10%. These concentrations are substantial, suggesting the ingredient is typically included at efficacious percentages rather than being merely 'dusted' for marketing claims.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

This extract is commonly supplied as a 20% concentration in a water- and glycerin-blend, affirming its water-soluble nature. Aqueous and hydroalcoholic extracts are typical forms. No specific optimal pH range for stability was identified in the provided data.

Safety

Safety Profile

CIR Status
Safe as used
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has concluded that Oenothera Biennis (Evening Primrose) Oil and Hydrogenated Evening Primrose Oil are safe for use in cosmetics. As a botanical extract, it is generally considered mild and well-tolerated, carrying a low risk of sensitization. While mild allergic reactions, such as irritation or itching, are possible in sensitive individuals, regulatory authorities generally permit its use. It is crucial to distinguish its safe topical application from the FDA's 'Inadequate basis for expectation of safety' status for oral Evening Primrose Oil supplements.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Oenothera Biennis Extract is a valuable botanical ingredient offering comprehensive benefits for skin health, including significant moisturizing, anti-inflammatory, and anti-aging effects, supported by both recommended use levels and in vitro scientific evidence.

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