Science
Mechanism of Action
Oenanthe Javanica Extract functions as a robust antioxidant by scavenging reactive oxygen species, including superoxide anion radicals and hydrogen peroxide, a benefit attributed to its rich phenolic and flavonoid composition. It exhibits significant anti-inflammatory action by inhibiting inflammatory cytokines, notably reducing TNF-α and COX-2 expressions in UVB-induced inflammation. Furthermore, this extract combats signs of aging and wrinkles by protecting against collagen degradation through decreased MMP-1 and MMP-3 activity, while simultaneously promoting the expression of collagen I and III. It also inhibits elastase and hyaluronidase enzymes, contributing to skin elasticity and hydration. Collectively, these actions provide effective photoprotection against UVB radiation, attenuating collagen disruption and inflammatory responses.
Research
Clinical Evidence
Medium confidence1%
Transparency
Dusting Analysis
The Formula
Formulation
Stability
A 0.8% extract in a hydrogel carrier maintained its optimal pH (4.5-5.5) and physical appearance for 30 days without microbial growth.
Safety
Safety Profile
While general toxicity studies indicate no acute or genetic toxicity, a rare case of irritant contact dermatitis was reported in a patient after applying fresh crushed Oenanthe javanica to the skin, resulting in edematous erythema, bullae, and burning pain. This suggests a potential for irritation, though specifically with the raw plant material.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Oenanthe Javanica Extract is a valuable ingredient, offering significant antioxidant, anti-inflammatory, and anti-aging benefits, alongside robust photoprotective capabilities for comprehensive skin health.
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References
Sources