Science
Mechanism of Action
As a surfactant, Octoxynol-13 reduces the surface tension between different substances, allowing immiscible components like oil and water to combine and form stable emulsions. This property also enhances its cleansing action, enabling water to effectively lift and rinse away oily residues and impurities. Furthermore, as a longer-chain Octoxynol, it acts as a solubilizing agent, integrating poorly soluble ingredients into cosmetic solvents.
Research
Clinical Evidence
Insufficient-data confidenceN/A
Key findings
- 01 Key studies for Octoxynol-13 have focused on its safety profile: In rabbit dermal irritation tests, 0.5 ml applied under an occlusive patch to intact or abraded skin was not deemed a primary dermal irritant.
- 02 A human skin sensitization potential study involving 50 subjects concluded that Octoxynol-13 did not induce sensitization.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Octoxynol-13 demonstrates optimal stability within a pH range of 5.0 to 8.0. Decomposition occurs upon heating, emitting acrid smoke and fumes.
Conflicts
- strong oxidizing agents
- strong reducing agents
Safety
Safety Profile
The CIR Expert Panel consistently deems Octoxynol-13 safe for use in both rinse-off and leave-on cosmetic products, a conclusion reaffirmed in amended reports from 2004 and 2023. It is recommended that formulations ensure the final product is non-irritating. Manufacturing by-products such as 1,4-dioxane, ethylene oxide, or unreacted C9 phenols may be present in trace amounts, but these can be effectively managed through standard purification processes.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Octoxynol-13 is a valuable functional ingredient due to its effective emulsifying, cleansing, and solubilizing properties, coupled with a low risk of irritation and sensitization across all skin types.
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References
Sources