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Moumoujus

OCTANEDIOL.

Valuable CAS 629-41-4 / PLASTICISER

Octanediol, often recognized as Caprylyl Glycol, is a versatile aliphatic diol valued for its multi-functional role in precision skincare. It acts primarily as a humectant and emollient, significantly contributing to skin hydration and barrier integrity, while also offering antimicrobial benefits and boosting preservative efficacy in formulations.

Summary

Humectant Emollient Antimicrobial Preservative Booster Skin Conditioning Hair Conditioning Emulsifier Penetration Enhancer Deodorant Skin Barrier Support Microflora Balancing

Science

Mechanism of Action

Octanediol operates through several key mechanisms: as a humectant, it attracts and binds moisture to the skin, enhancing hydration and promoting a smoother complexion. Its emollient properties soften the skin surface and reinforce the skin barrier function. Furthermore, Octanediol exhibits broad-spectrum antimicrobial activity against bacteria and fungi, complementing and boosting the effectiveness of other preservatives. It can also function as an emulsifier to stabilize cosmetic solutions and acts as a penetration enhancer, facilitating deeper delivery of other active ingredients into the skin while contributing to a balanced skin microflora.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 A 5% concentration of 1,2-octanediol lotion was found to be an effective pediculicide for treating head louse infestations, demonstrating comparable efficacy to formulations containing 20% alcohol.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Octanediol maintains broad efficacy across a wide pH range, making it highly adaptable in diverse cosmetic formulations. It exhibits strong stability against degradation from air and light exposure, though its integrity may be compromised in the presence of strong acids, strong bases, or potent oxidizing agents.

Synergies

  • Preservatives (enhanced efficacy)
  • Other active ingredients (improved skin penetration)

Conflicts

  • strong acids
  • strong bases
  • oxidants

Safety

Safety Profile

CIR Status
Safe as used
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel concluded that 1,2-Octanediol (Caprylyl Glycol) and related 1,2-glycols are safe for use in cosmetic formulations under current practices. It's crucial to note that while the EPA Safer Choice program has verified 1,2-Octanediol as a chemical of low concern, the safety data for the 1,8-Octanediol isomer were deemed insufficient for a definitive safety determination by the CIR panel. Studies on a 1,2-hexanediol/caprylyl glycol mixture, at concentrations up to 15%, did not induce sensitization in human subjects.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Octanediol is a valuable, multi-functional ingredient known for its hydrating, emollient, and antimicrobial properties, enhancing both product formulation stability and overall skin health across various skin types.

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