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OCTAHYDRO-2,5,5-TRIMETHYL-2-NAPHTHOL.

Optional CAS 71832-76-3 / PERFUMING

OCTAHYDRO-2,5,5-TRIMETHYL-2-NAPHTHOL is a synthetic aroma compound valued for its sophisticated amber fragrance, featuring notes reminiscent of aged ambergris alongside tobacco, leather, and musk. It is primarily utilized in cosmetics and personal care products to impart a distinct and elegant scent.

perfuming

Science

This ingredient functions predominantly as a perfuming agent, interacting with olfactory receptors to create its characteristic aroma. It does not possess active dermatological mechanisms relevant to skin physiology or therapeutic benefit; its role is purely sensory.


Research

High confidence
Effective range 0.02–0.79%
Optimal

N/A

Key findings

  1. 01 RIFM assessments consistently indicate that various concentrations, ranging from 0.02% (in axillary products) to 0.79% (in hair products with hand contact), are acceptable for use.
  2. 02 These RIFM studies confirm no safety concern regarding skin sensitization or genotoxicity across the specified concentration levels for products applied to the face, lips, and fine fragrances, among others.

Transparency

Not commonly dusted

As a fragrance ingredient, this compound is not typically associated with dusting concerns in skincare formulations.


The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

This compound exhibits very low water solubility, with reported values ranging from 28.09 mg/L to 584.5 mg/L at 24-25°C. It is readily soluble in alcohol and demonstrates strong oil solubility, indicated by a LogP value of approximately 3.8 to 4.6.


Safety

CIR Status
Not reviewed
Max tested
0.79%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel does not review this ingredient, as its primary function is fragrance; its safety is evaluated by the Research Institute for Fragrance Materials (RIFM). RIFM has concluded it can be used safely in everyday products at current levels, without concern for genotoxicity or skin sensitization. However, some classifications indicate a potential for irritation to eyes, respiratory system, and skin (R 36/37/38) and specifically 'Causes skin irritation' (H315). The maximum acceptable concentration, as per IFRA standards, is 0.79% in products applied to hair with some hand contact.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Medium
Comedogenicity Unknown

Our Assessment

Optional

An aromatic compound primarily used for its elegant amber fragrance, deemed safe by RIFM within specified concentrations for various cosmetic applications, though some irritation potential has been noted.


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