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Moumoujus

OCIMUM GRATISSIMUM HERB OIL.

Valuable CAS 91770-38-6 / PERFUMING

Ocimum Gratissimum Herb Oil, also known as Clove Basil oil, is a naturally derived essential oil recognized for its multi-faceted benefits. Rich in active compounds, it delivers potent antibacterial, anti-inflammatory, and antioxidant properties, making it a precise solution for addressing various skin concerns, particularly those involving blemishes.

Summary

Antibacterial Anti-inflammatory Antioxidant Fragrance

Science

Mechanism of Action

The primary mechanism of Ocimum Gratissimum Herb Oil stems from its high eugenol content, which can constitute up to 85% of its composition in certain chemotypes. Eugenol acts by altering bacterial cell membranes, disrupting cytoplasm, affecting critical ion and ATP transport, and inhibiting bacterial enzymes, leading to microbial cell death. Complementary antioxidant and anti-inflammatory effects are attributed to compounds like flavonoids and phenols, which scavenge free radicals, chelate metal ions, and block enzyme systems involved in free radical generation.

Research

Clinical Evidence

Medium confidence
Effective range 20–250%
Optimal

2%

Key findings

  1. 01 At a 2% v/v concentration, this herb oil demonstrated remarkable antibacterial efficacy against common wound-infecting organisms, including those implicated in boils and pimples. Its performance often exceeded that of commercial antiseptic products, without causing skin irritation.
  2. 02 In vitro studies revealed a progressive inhibition of bacterial growth across a concentration range of 20-250 µg/ml.

Transparency

Dusting Analysis

Not commonly dusted

As an active essential oil with specific efficacy and safety profiles at defined concentrations, Ocimum Gratissimum Herb Oil is intended for precise formulation as an active ingredient and is not typically 'dusted' at insignificant levels.

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

The chemical composition of Ocimum Gratissimum essential oil can exhibit variability influenced by genetic, environmental, and agronomic factors. The choice of base also impacts its efficacy; greater antibacterial activity has been observed in hydrophilic bases compared to lipophilic ones.

Conflicts

  • Antibacterial activity may be reduced when formulated in lipophilic bases compared to hydrophilic bases.

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
2%
Sensitization risk Moderate

Topical application of Ocimum Gratissimum Herb Oil at 2% v/v has been shown to cause no skin irritation. However, concentrations of 5% v/v or higher may induce skin-irritating effects or contact dermatitis, particularly in individuals with sensitive skin, unless formulated in specific bases such as petrolatum.

Your Skin

Skin Compatibility

No Normal
No Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Ocimum Gratissimum Herb Oil is a valuable natural ingredient for targeted skincare, offering potent antibacterial and anti-inflammatory benefits for blemish-prone skin when precisely formulated at a maximum concentration of 2% v/v to ensure optimal efficacy and safety.

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