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Moumoujus

OCIMUM AMERICANUM LEAF/STEM OIL.

Valuable CAS 91845-26-0 / FRAGRANCE, PERFUMING

Ocimum Americanum Leaf/Stem Oil, derived from American Basil, is a botanical extract recognized for its potent antioxidant, anti-inflammatory, and antimicrobial properties. It offers multifaceted benefits for skin health, traditionally utilized to address various dermal concerns.

Summary

Antioxidant Anti-inflammatory Antimicrobial Antibacterial Antifungal Fragrance

Science

Mechanism of Action

This essential oil combats oxidative stress by effectively neutralizing reactive oxygen and nitrogen species, thereby mitigating cellular damage and inflammation. It reduces inflammation and edema through the inhibition of free radical generation. Furthermore, its antimicrobial action stems from disrupting microbial cell membranes, inhibiting biofilm formation, and increasing membrane permeability, leading to intracellular leakage and antibacterial and antifungal effects.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

3%

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

The inherent pH of Ocimum americanum essential oil is acidic, typically measuring 3.39 ± 0.31, which may influence its formulation stability. For optimal shelf life, it should be stored in cool, dry conditions, in tightly sealed containers, protected from heat and light, for up to 12 months or longer. Variations in essential oil composition and yield are influenced by factors such as variety, developmental stage, harvest season, distillation method, and environmental conditions. It can be effectively formulated into microemulsions.

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
3%
Sensitization risk Moderate

Specific safety assessments from CIR, SCCS, or FDA for Ocimum Americanum Leaf/Stem Oil are currently unavailable. The GHS Classification (OSHA HCS) indicates no identified hazards, hazard statements, or precautionary statements, and oral, dermal, and inhalation toxicity were not determined. A maximum topical concentration of 3% is inferred from human skin irritation tests on a related species (Ocimum basilicum), where 3% in a microemulsion was safe and well-tolerated, but 5% caused irritation. Acute toxicity studies of the hydrodistilled residue by-product of O. americanum have shown it to be safe.

Your Skin

Skin Compatibility

No Normal
No Dry
Yes Oily
Yes Sensitive
Irritancy Medium
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Ocimum Americanum Leaf/Stem Oil is a valuable ingredient, delivering significant antioxidant, anti-inflammatory, and antimicrobial benefits to the skin, provided its formulation adheres to a maximal concentration of 3% for optimal safety and efficacy.

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