Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle

NOPYL ACETATE.

Questionable CAS 128-51-8 / FRAGRANCE

Nopyl Acetate is a synthetic aroma compound valued for imparting sweet, woody, fruity, floral, and citrus notes to cosmetic and personal care products. While it enhances the sensory experience, its usage is associated with a risk of contact allergy and irritation.

Fragrance

Science

Nopyl Acetate functions exclusively as a fragrance ingredient, contributing a complex aromatic profile to cosmetic products. Its molecular structure allows for the perception of sweet, woody, fruity, floral, and citrus notes, thereby enhancing the overall scent and diffusion within a formulation. It does not exert any direct physiological effects on the skin.


Research

Low confidence
Effective range 0.02–0.4%
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH 3 – 10
0 7 14

Stability

Nopyl Acetate demonstrates robust stability and diffusion within aroma chemical systems, maintaining integrity across a pH range of 3 to 10. Degradation may occur in highly alkaline environments, specifically at pH 11 and 14. It tolerates heat during formulation but requires storage in sealed containers, away from direct sunlight and temperatures exceeding 40°C.

Conflicts

  • Extremely alkaline systems (e.g., powder detergents, bleach)
  • Temperatures above 40°C

Safety

CIR Status
Not reviewed
Sensitization risk High

The European Commission's Scientific Committee on Consumer Safety (SCCS) reports evidence of Nopyl Acetate causing contact allergy in humans, potentially leading to irritation and allergic skin reactions. It is also classified as a serious eye irritant and may be harmful if ingested or absorbed dermally. Suggested application levels in body care products range from 0.02% to 0.40%.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Medium
Comedogenicity Unknown

Our Assessment

Questionable

Nopyl Acetate functions solely as a fragrance component; however, its documented risk for contact allergy and irritation renders its use questionable for precision skincare formulations focused on dermal health.


Related

Finding similar ingredients…