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NOPOL.

Questionable CAS 128-50-7 / PERFUMING

NOPOL is an aroma chemical primarily utilized for its fresh, woody, floral, and subtly rosy fragrance profile in various cosmetic and personal care products. While some sources suggest it possesses antioxidant properties, its direct skincare efficacy is not extensively substantiated.

Fragrance Antioxidant (potential)

Science

Predominantly, NOPOL functions by interacting with olfactory receptors, thereby imparting a specific scent to products. It has also been noted to exhibit antioxidant capabilities, which may contribute to the skin's defense against environmental damage, though a detailed mechanistic explanation for this specific ingredient's action on skin remains largely undefined in available research.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Commonly dusted

Given NOPOL's primary classification as a fragrance ingredient and the limited, undefined nature of its reported antioxidant mechanism on skin, combined with a lack of specific clinical efficacy studies, its inclusion solely for antioxidant claims in a precision skincare product could be considered a form of 'dusting' rather than a data-driven active ingredient choice.


The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

NOPOL is described as a stable aroma chemical, demonstrating consistent performance under high-temperature and alkaline conditions. This stability supports its use across a diverse range of industrial and home fragrance applications.


Safety

CIR Status
Not reviewed
Max tested
0.08%
Sensitization risk Moderate

NOPOL is generally considered relatively safe for use, with no significant safety concerns reported beyond its irritant potential. Hazard statements explicitly indicate it 'Causes skin irritation' and 'Causes eye irritation', and it is listed on California Prop. 65. A maximum usage level of 8.0000% has been noted for fragrance concentrates. There are no specific CIR or SCCS safety assessments available for NOPOL when specifically evaluated as a skincare ingredient.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Questionable

While NOPOL imparts an appealing fragrance and may possess antioxidant properties, the explicit warnings regarding skin and eye irritation, coupled with limited robust clinical evidence for its targeted skincare benefits, make its inclusion in precision skincare formulations questionable.


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