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NONYL NONOXYNOL-49.

Questionable CAS 9014-93-1 / CLEANSING, SURFACTANT - CLEANSING

NONYL NONOXYNOL-49 is a synthetic nonionic surfactant functioning as a versatile agent in cosmetic formulations. It effectively cleanses by emulsifying oils and impurities, while also stabilizing product emulsions to maintain integrity and enhance performance.

Cleansing Agent Emulsifier Solubilizer

Science

As a nonionic surfactant, NONYL NONOXYNOL-49 lowers the surface tension between disparate phases, enabling the solubilization of oils into water and the stabilization of oil-in-water or water-in-oil emulsions. This property allows it to dislodge and remove surface debris and oils from the skin, acting as an effective cleansing agent.


Research

Insufficient-data confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Safety

CIR Status
Safe with restrictions
Max tested
5%
Sensitization risk Low

The CIR Expert Panel has deemed the broader family of Nonoxynols, including this variant, safe for use in rinse-off cosmetic products and safe in leave-on products at concentrations up to 5%, based on human skin irritation and sensitization data. However, Nonoxynols are prohibited in cosmetics and personal care products marketed in the European Union, primarily due to environmental concerns regarding their persistence and potential for endocrine disruption in ecological species. It is important to note that the FDA has issued warnings specifically for Nonoxynol-9 in vaginal contraceptive products due to irritation and lack of HIV/STD protection, which is a distinct application context.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Medium
Comedogenicity Unknown

Our Assessment

Questionable

While NONYL NONOXYNOL-49 is a functional cleansing and emulsifying agent deemed safe by CIR at concentrations up to 5% for consumer use, its medium irritancy potential and the ban in the EU for environmental reasons make it a questionable choice for precision skincare formulations.


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