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NONAPEPTIDE-2.

Valuable / HAIR CONDITIONING, SKIN CONDITIONING

NONAPEPTIDE-2 is a synthetic peptide within the nonapeptide family, poised to offer multifaceted benefits for skin health. It is believed to engage in various biological pathways to support skin integrity, including collagen synthesis, melanin regulation, and defense against environmental stressors.

Anti-aging Skin brightening Anti-pigmentation Anti-inflammatory Antioxidant Hydration Barrier support Wound healing

Science

NONAPEPTIDE-2 is thought to exert its actions through several key mechanisms. It may help in mitigating inflammation and promoting the skin's natural healing processes. The peptide is also suggested to stimulate collagen production, which is crucial for enhancing skin elasticity and diminishing the appearance of fine lines. Furthermore, it appears to inhibit melanin synthesis, contributing to a brighter complexion and reducing hyperpigmentation and dark spots. NONAPEPTIDE-2 also aims to boost skin hydration by supporting moisture regulation and fortifying the skin's barrier function, while providing antioxidant defense against external aggressors. Broader nonapeptide research suggests additional roles in alleviating UV-A-induced oxidative stress, restraining pro-inflammatory cytokine activity, protecting mitochondrial health, and maintaining cellular autophagy, which collectively could contribute to delaying photoaging.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

No specific data available to suggest this ingredient is commonly 'dusted' or used at ineffective concentrations.


The Formula

Solubility
Water
Optimal pH 3.5 – 7
0 7 14

Stability

Specific optimal pH range and stability data for NONAPEPTIDE-2 are not directly available. However, information for the related Nonapeptide-1 indicates water solubility and stability within a pH range of 3.5 to 7.0, suggesting similar characteristics may apply.


Safety

CIR Status
Not reviewed
Sensitization risk Low

No specific safety assessments for NONAPEPTIDE-2 by regulatory bodies like CIR, SCCS, or FDA were identified. Nevertheless, nonapeptides, and peptides in general, are widely regarded as ingredients with a low risk of toxicity or adverse reactions in cosmetic applications.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

NONAPEPTIDE-2 holds promising potential across several skin health categories, including anti-aging, brightening, and protective benefits, though direct clinical evidence specific to this peptide is currently limited and often extrapolated from broader nonapeptide research.


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