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NONAN-2-ONE.

Avoid CAS 821-55-6 / PERFUMING

Nonan-2-one is an organic ketone primarily recognized for its distinct aroma, functioning as a fragrance and flavoring agent. While widely used in perfumery and food products, it has no identified beneficial action on the skin and is classified as a potential irritant.

Fragrance Ingredient Masking Agent

Science

This compound interacts with olfactory receptors, contributing a scent profile, particularly a fruity, floral, or cheesy note depending on concentration. No specific beneficial biological mechanism of action on the skin has been identified; its primary role in cosmetic formulations is limited to scenting products. However, it is recognized to potentially cause irritation to skin and eyes.


Research

Insufficient-data confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

Nonan-2-one is not an ingredient typically 'dusted' or exaggerated for skincare benefits, as it has no identified therapeutic efficacy for the skin.


The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Conflicts

  • Many acids and bases (can liberate heat and flammable H2 gas)
  • Reducing agents (e.g., hydrides, alkali metals, nitrides)
  • Isocyanates
  • Aldehydes (reacts violently)
  • Cyanides
  • Peroxides
  • Anhydrides
  • Nitric acid (HNO3)
  • Nitric acid + Hydrogen peroxide (HNO3 + H2O2)
  • Perchloric acid (HClO4)

Safety

CIR Status
Not reviewed
Max tested
3%
Sensitization risk High

The maximum concentration of 3.00% refers to its use in fragrance concentrates. While generally recognized as safe (GRAS) for food flavoring by FEMA and FDA within specific limits, its safety profile for topical skincare is distinct. The Research Institute for Fragrance Materials (RIFM) has concluded its safe use in everyday products under current levels for fragrance purposes. However, it is classified by GHS as Skin Irritation Category 2 and Eye Irritation Category 2, indicating a clear potential for irritation to the skin, eyes, and respiratory system. The Cosmetic Ingredient Review (CIR) has not reviewed this ingredient.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Avoid

Nonan-2-one provides no discernible skincare benefits and presents a high risk of skin irritation, making it unsuitable for precision skincare formulations.


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