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NICOTINOYL SH-PENTAPEPTIDE-19.

Insufficient Data CAS - / SKIN CONDITIONING

NICOTINOYL SH-PENTAPEPTIDE-19 is a biotechnologically advanced peptide, engineered as a reaction product of niacin and sh-pentapeptide-19. It acts as a sophisticated cellular messenger, engaging the skin's inherent repair pathways to promote regeneration and strengthen structural integrity.

Skin Conditioning Anti-aging Skin Regeneration Support Collagen Synthesis Enhancer Elasticity Booster Complexion Refinement Skin Barrier Protection Anti-glycation Agent Cellular Energizer

Science

This innovative ingredient functions as a potent signaling peptide, initiating the skin's intrinsic repair mechanisms. It is designed to stimulate the regeneration of mature skin, enhancing its structure and visibly diminishing the appearance of fine lines and wrinkles. The ingredient also contributes to a refined skin complexion and improved elasticity. Leveraging its nicotinoyl component, it is understood to upregulate collagen production in fibroblast cultures, mitigate elevated dermal glycosaminoglycans often associated with photodamage, and augment the synthesis of crucial epidermal proteins such as keratin, filaggrin, and involucrin. Furthermore, it exerts anti-glycation effects, counteracting skin sallowness, while simultaneously boosting cellular energy and impeding cellular senescence.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Unknown
Optimal pH N/A
0 7 14

Safety

CIR Status
Not reviewed
Sensitization risk Unknown

Formal review by the Cosmetic Ingredient Review (CIR) Expert Panel is pending, and publicly available SCCS or FDA statuses are not established for this specific compound. Paula's Choice has not yet assigned a rating, awaiting further research. However, INCI Beauty reports no adverse penalties across its safety assessments for this ingredient.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Insufficient Data

NICOTINOYL SH-PENTAPEPTIDE-19 presents a compelling mechanistic profile for comprehensive anti-aging and skin conditioning; however, comprehensive clinical efficacy data and full regulatory safety reviews are presently limited, necessitating further investigation.


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