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Moumoujus

NICOTINOYL SH-DECAPEPTIDE-9.

Valuable CAS - / SKIN CONDITIONING, SKIN PROTECTING

NICOTINOYL SH-DECAPEPTIDE-9 is a sophisticated recombinant human peptide engineered to mimic the natural protein endorphin. This innovative ingredient is designed to actively promote epidermal regeneration and significantly boost key collagen synthesis, aiming to visibly enhance skin elasticity, firmness, and reduce the appearance of wrinkles, potentially offering additional antioxidant protection.

Summary

Skin conditioning Anti-aging Collagen booster Epidermal regeneration Elasticity enhancer Firming agent Antioxidant

Science

Mechanism of Action

The 'sh-decapeptide-9' component, structurally identical to human endorphin, functions by activating the skin's intrinsic repair mechanisms. In vitro investigations reveal its capacity to enhance epidermal regeneration and stimulate the synthesis of collagen types I and III, alongside other vital skin proteins, thereby improving structural integrity. The 'nicotinoyl' moiety is hypothesized to contribute antioxidant and protective benefits to the skin, complementing the peptide's regenerative actions.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Unknown
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

While NICOTINOYL SH-DECAPEPTIDE-9 itself has not been reviewed by organizations like CIR, related peptides, such as Cyclized Hexapeptide-9, are recognized for their exceptionally high safety profiles. Preliminary testing on a similar novel peptide with nicotinic activity reported it to be non-irritating and non-allergenic, suggesting a favorable safety outlook.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

This advanced peptide demonstrates significant potential for enhancing skin regeneration and structural integrity based on robust mechanistic and in vitro data, positioning it as a valuable asset for targeted anti-aging formulations.

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