Science
Mechanism of Action
Operating as a potent cellular messenger, Nicotinoyl Dipeptide-24 activates the skin’s inherent repair mechanisms. It specifically intervenes in melanin production by suppressing Microphthalmia-Associated Transcription Factor (MITF) and inhibiting Tyrosinase 1 and 2 enzymes, while also preventing melanosome transfer from melanocytes to keratinocytes. This leads to a more unified and brighter complexion with reduced hyperpigmentation and dark spots. Furthermore, this innovative peptide promotes robust collagen generation and delivers anti-inflammatory benefits, contributing to a visible anti-wrinkle effect. Its niacinamide component also fortifies the skin barrier through increased epidermal protein synthesis, provides antioxidant and antiglycation protection, and reduces inflammation and oxidative stress.
Research
Clinical Evidence
High confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Nicotinoyl peptide derivatives exhibit commendable long-term stability. The pure powder form of Nicotinoyl Dipeptide-24 is stable for up to 24 months when stored optimally at -20℃ to -15℃ in a freezer, protected from light and air.
Safety
Safety Profile
While formal CIR review is pending for Nicotinoyl Dipeptide-24, closely related nicotinoyl peptide derivatives have consistently demonstrated minimal cytotoxicity at concentrations up to 100 µM and no reported allergic reactions, suggesting a favorable safety profile.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A valuable multi-functional peptide derivative that targets signs of aging, uneven skin tone, and supports skin barrier health with a favorable safety profile.
Related
Similar Ingredients
Finding similar ingredients…
References
Sources