Science
Mechanism of Action
This ingredient acts on multiple pathways to improve skin tone and texture. It directly reduces melanin synthesis by suppressing Microphthalmia-Associated Transcription Factor (MITF) production and inhibiting Tyrosinase 1 and 2 enzymes, crucial for pigment formation. Furthermore, it prevents the transfer of melanosomes from melanocytes to keratinocytes, effectively brightening the skin and diminishing discolorations. As a peptide, it also stimulates the skin's natural repair mechanisms, promotes the regeneration of mature skin cells, and strengthens skin structure, leading to a visible reduction in wrinkles and improved elasticity by mimicking natural collagen fragments.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
This ingredient maintains stability for 24 months when stored between -20°C and -15°C in a freezer. It must be protected from light and kept air-proofed when not in use. General peptide stability challenges include enzymatic degradation, oxidation, light exposure, and temperature sensitivity.
Safety
Safety Profile
Specific safety assessments by major regulatory bodies such as CIR, SCCS, or FDA are not available for Nicotinoyl Dipeptide-23. Publicly available data does not include GHS classifications, hazard statements, or specific toxicity information, leading to an unknown sensitization risk.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Nicotinoyl Dipeptide-23 is a valuable multi-functional ingredient that effectively targets hyperpigmentation through multiple pathways while simultaneously promoting skin regeneration and improving elasticity.
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