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NICOTIANA TABACUM FLOWER EXTRACT.

Questionable CAS 84961-66-0 / PERFUMING

Nicotiana Tabacum Flower Extract is derived from tobacco blossoms, prized primarily for its aromatic qualities in perfumery. Beyond its fragrant profile, this extract also delivers notable antioxidant benefits and demonstrates antimicrobial properties against specific bacteria and fungi. However, its use in precision skincare requires careful consideration due to potential sensitization.

perfuming antioxidant antimicrobial

Science

This extract functions on the skin through a blend of active compounds, including alkaloids, flavonoids, and essential oils. Its antioxidant capacity stems from phenolic compounds like flavonols and anthocyanins, which neutralize free radicals. Furthermore, it exhibits antimicrobial action, targeting pathogens such as Staphylococcus aureus and Candida albicans, contributing to a cleaner skin surface.


Research

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 In in-vitro assessments, ethanol and methanol extracts of tobacco flowers exhibited a Minimum Inhibitory Concentration (MIC) of 32% and a Minimum Bactericidal Concentration (MBC) of 64% against Staphylococcus aureus and Candida albicans. An N-Hexane extract also showed MIC and MBC of 64% against C. albicans.

Transparency

Not commonly dusted

The Formula

Solubility
Both
Optimal pH 2 – 4
0 7 14

Stability

The flavylium ions, critical components for the extract's color and stability, are optimal under highly acidic conditions. Raising the pH to weakly acidic ranges (pH 2-4) shifts these structures to blue quinoidal forms. Neutral to alkaline environments (pH 5-7+) lead to degradation, forming colorless carbinol pseudobases and chalcones. To preserve integrity, avoid temperatures exceeding 60°C during formulation.


Safety

CIR Status
Not reviewed
Sensitization risk Moderate

While not listed as banned or restricted by EU cosmetics regulations (with the exception of isolated nicotine), this extract carries a risk of skin irritation, allergic reactions, and contact dermatitis. A preliminary patch test is strongly recommended prior to broad application. Specific data regarding its topical use during pregnancy or breastfeeding is currently unavailable.


Your Skin

No Normal
No Dry
Yes Oily
No Sensitive
Irritancy Medium
Comedogenicity Low

Our Assessment

Questionable

Despite possessing appealing aromatic, antioxidant, and antimicrobial properties, its unreviewed safety status, medium irritancy risk, and lack of comprehensive topical efficacy data make its general application in precision skincare questionable without further research and rigorous testing.


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References