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NICOTIANA BENTHAMIANA R-(S-CLOSTRIDIUM BOTULINUM POLYPEPTIDE-1 S-SPIDER OLIGOPEPTIDE-1 SH-OLIGOPEPTIDE-1).

Insufficient Data / SKIN CONDITIONING

This advanced recombinant polypeptide complex is biosynthesized in Nicotiana benthamiana and integrates bio-active sequences inspired by Clostridium botulinum, spider silk, and epidermal growth factor. It is engineered to address multiple signs of skin aging by targeting dynamic wrinkles, enhancing skin elasticity, and stimulating cellular regeneration.

Anti-aging Wrinkle reduction (dynamic) Skin firming Skin elasticity enhancement Cellular regeneration Collagen stimulation Elastin stimulation Skin barrier support

Science

This complex acts via a multi-modal biological mechanism. The *Clostridium botulinum*-derived sequence is designed to modulate neuro-muscular signaling, aiming to reduce the appearance of dynamic facial wrinkles. Concurrently, the *S-Spider Oligopeptide-1* component is theorized to provide structural support and film-forming properties, contributing to enhanced skin elasticity and barrier integrity. The *SH-Oligopeptide-1 (Epidermal Growth Factor, EGF)* fraction further stimulates epidermal growth factor receptors, promoting cellular proliferation, collagen and elastin synthesis, and accelerated tissue regeneration.


Research

Insufficient-data confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

As a novel, highly complex biotechnologically produced ingredient, specific data regarding 'dusting' or common misuse concentrations is not publicly established. Its advanced nature suggests a focused and precise application rather than arbitrary inclusion in formulations.


The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Peptides are generally sensitive to extreme pH values, high temperatures, and enzymatic degradation. Specific formulation guidelines are crucial for maintaining the activity and structural integrity of this complex polypeptide.

Synergies

  • Antioxidants
  • Humectants (to support skin hydration and absorption)
  • Other compatible signaling peptides

Conflicts

  • Strong acids/bases
  • High temperatures
  • Proteolytic enzymes
  • Certain harsh solvents that may denature proteins

Safety

CIR Status
Not Reviewed
Sensitization risk Unknown

Given its novel and complex nature, comprehensive safety assessments are paramount. While individual peptide classes like EGF are generally well-studied, the unique recombinant fusion structure of this particular ingredient necessitates specific toxicological and sensitization evaluations for human dermal application.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Insufficient Data

This innovative, bioengineered polypeptide complex holds significant theoretical promise for comprehensive anti-aging benefits due to its multi-target mechanism, but currently lacks publicly available clinical data for a definitive efficacy and safety assessment.


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