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Ingredient directory

Nicotiana Benthamiana Hexapeptide-40 Sh-polypeptide-9

This innovative fusion peptide is biosynthesized using transgenic Nicotiana benthamiana, precisely mimicking the human gene that codes for Vascular Endothelial Growth Factor A (VEGF-A). Functioning as a signaling molecule, it aims to activate the skin's inherent repair mechanisms, with potential applications in enhancing skin firmness and stimulating cellular regeneration.

Directory entry · Individual source review pending

This profile is awaiting an individual source review. Treat its ratings, dose estimates and compatibility labels as provisional; they are not medical advice or proof of a finished product’s effects.

Hair Conditioning Peptide

Science

NICOTIANA BENTHAMIANA HEXAPEPTIDE-40 SH-POLYPEPTIDE-9 is engineered to be identical to human VEGF-A at the genetic level, acting as a potent signaling molecule. Peptides of this nature typically interact with cellular pathways to trigger endogenous repair processes. This can encompass the promotion of collagen synthesis, improvement in dermal firmness and elasticity, and acceleration of cellular turnover and regenerative cycles.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

No data suggests this ingredient is commonly 'dusted' or used at ineffective concentrations to inflate claims without substantiation.


The Formula

Solubility
Unknown
Optimal pH N/A
0 7 14

Safety

CIR Status
Not reviewed
Sensitization risk Unknown

Specific safety assessments by CIR, SCCS, or FDA for NICOTIANA BENTHAMIANA HEXAPEPTIDE-40 SH-POLYPEPTIDE-9 are currently unavailable. However, similar Nicotiana benthamiana-derived peptide ingredients are generally considered safe for topical use. As a precautionary measure, patch testing is advisable to mitigate potential risks of irritation, erythema, pruritus, or allergic responses.


Your Skin

No Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Insufficient Data

While exhibiting a promising mechanism based on VEGF-A mimicry, the absence of specific clinical efficacy data and comprehensive safety reviews for this exact ingredient limits a definitive recommendation for precision skincare.


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