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NICOTIANA BENTHAMIANA HEXAPEPTIDE-40 SH-POLYPEPTIDE-2.

Valuable / HAIR CONDITIONING, SKIN CONDITIONING

This fusion peptide, derived from genetically modified Nicotiana benthamiana, acts as a potent biomimetic Thioredoxin-1, signaling endogenous skin repair mechanisms. It is designed to combat photoaging, reduce wrinkles, and enhance overall skin hydration and elasticity.

Skin-Conditioning Agent Hair-Conditioning Agent

Science

This ingredient functions as a biomimetic Thioredoxin-1 (TRX-1) protein, providing protection against inflammation and photoaging by neutralizing reactive oxygen species (ROS) and mitigating the effects of matrix metalloproteinase-9 (MMP-9) and tumor necrosis factor-alpha (TNFa) induced by radiation. As a signaling peptide, it activates the skin's natural repair mechanisms, stimulating the regeneration of mature skin, strengthening its structural integrity, and visibly reducing wrinkles. Furthermore, it acts as a skin conditioning agent, maintaining hydration, enhancing suppleness, and contributing to a softer, more elastic complexion by optimizing moisture levels, thereby minimizing the appearance of fine lines and wrinkles.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

Insufficient data available to determine dusting prevalence or thresholds for this ingredient.


The Formula

Solubility
Unknown
Optimal pH N/A
0 7 14

Safety

CIR Status
Not reviewed
Pregnancy
Caution
Sensitization risk Low

While generally considered safe for topical application in cosmetic products, comprehensive data regarding its usage during pregnancy and breastfeeding are currently unavailable. Consultation with a healthcare professional is recommended for individuals in these specific populations.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

This biomimetic peptide offers a robust mechanism for protecting skin against environmental stressors and promoting regeneration, making it a valuable asset for anti-aging and conditioning formulations, though further *in vivo* human studies would solidify its clinical efficacy.


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