Science
Mechanism of Action
This advanced fusion peptide is biosynthesized from the Nicotiana benthamiana plant, with its genetic blueprint designed to be identical to the human gene encoding Epidermal Growth Factor (EGF). Upon topical application, it acts as a cellular messenger, signaling the skin to activate its natural repair mechanisms. This process promotes cell regeneration and stimulates collagen production, contributing to improved skin elasticity, texture refinement, and a reduction in the visible signs of aging. It also aids in hydrating and softening dry or compromised skin, restoring suppleness.
Research
Clinical Evidence
Low confidenceN/A
Key findings
- 01 A study utilizing 10 µg/g of sh-oligopeptide-1, a component of this ingredient, in a product targeting post-laser edema and hyperpigmentation, indicated no difference from the control group. The scientific community has also raised questions regarding the functional efficacy of sh-oligopeptide-1 as a true EGF.
- 02 This ingredient is reportedly part of a 15% 'growth factors' solution, marketed for age-support and visible skin damage repair. However, specific efficacy data for NICOTIANA BENTHAMIANA HEXAPEPTIDE-40 SH-OLIGOPEPTIDE-1 within this complex are not detailed.
Transparency
Dusting Analysis
Specific efficacy-driven concentration thresholds for NICOTIANA BENTHAMIANA HEXAPEPTIDE-40 SH-OLIGOPEPTIDE-1 are not clearly established in the provided data. While a related 'growth factors' solution is noted at 15%, the precise effective concentration for this individual fusion peptide remains undefined, making it challenging to identify dusting scenarios.
The Formula
Formulation
Stability
Typically supplied as a freeze-dried powder, preserving its integrity. It can be formulated alongside various vitamins and care substances.
Synergies
- Niacinamide (Vitamin B3)
- Panthenol (Vitamin B5)
- Vitamin E
Safety
Safety Profile
While sh-oligopeptide-1, a component of this fusion peptide, is authorized for general cosmetic use, its long-term safety profile remains largely uncharacterized. It is crucial to distinguish this cosmetic ingredient from 'active EGF,' which is classified as an unauthorized drug. Currently, no specific SCCS opinion is available for this ingredient. Overall, it is generally deemed safe for topical cosmetic applications, though further long-term data are needed.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This innovative plant-derived peptide presents potential anti-aging and skin-conditioning benefits; however, further specific efficacy data and long-term safety evaluations are required to provide a definitive assessment.
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References
Sources