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NEROL.

Valuable CAS 106-25-2 / PERFUMING

Nerol is a naturally occurring terpene alcohol recognized for its multifaceted benefits in skincare. It actively promotes skin regeneration and supports crucial components like collagen and hyaluronic acid, while also providing comprehensive anti-inflammatory, antioxidant, and antimicrobial protection.

perfuming antioxidant anti-inflammatory skin conditioning antimicrobial

Science

Nerol exerts its effects through several distinct mechanisms. It stimulates skin cell regeneration and enhances elasticity. Its antioxidant properties neutralize free radicals, potentially by activating the nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway, which is essential for maintaining collagen and hyaluronic acid levels. Nerol also helps balance sebum production, contributing to a less oily complexion, and its anti-inflammatory properties effectively soothe irritation and redness. Additionally, it exhibits antimicrobial and antiseptic actions, aiding in reducing breakouts and cleansing the skin, along with astringent qualities to minimize pore appearance and humectant capabilities for moisture retention.


Research

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 In vitro studies demonstrate that Nerol, when applied in non-toxic concentrations, successfully reinstates collagen content and hyaluronic acid levels in human dermal fibroblasts previously treated with dexamethasone, thereby mitigating glucocorticoid-induced skin aging via the Nrf2 signaling pathway.
  2. 02 Research indicates that neroli essential oil, a source of Nerol, acts as a potent anti-inflammatory agent effective against both acute and chronic inflammation, and possesses broad-spectrum antimicrobial properties against various bacteria and fungi.

Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Nerol, as a terpene, is prone to polymerization through oxidation. It also exhibits increased cyclization in acidic environments, suggesting careful pH control is necessary during formulation to maintain stability.

Conflicts

  • acids
  • oxidizing agents

Safety

CIR Status
Unknown
Sensitization risk Moderate

Undiluted Nerol applied directly to the skin has shown to cause moderate irritation, indicating a need for significant dilution in topical formulations. A patch test is strongly recommended, especially for individuals with sensitive skin. The potential presence of Geraniol, often a byproduct in synthesis processes, may contribute to allergenicity, although pure Nerol itself may not pose the same risk. General safety practices advise avoiding direct contact with skin and eyes, and refraining from inhaling vapor/spray.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Medium
Comedogenicity Low

Our Assessment

Valuable

Nerol presents as a valuable multi-functional ingredient offering significant anti-aging, anti-inflammatory, and antimicrobial benefits suitable for all skin types, provided it is properly diluted and formulated to minimize its moderate irritancy potential.


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