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NEOPENTYL GLYCOL DIPELARGONATE.

Valuable CAS 15834-05-6 / PLASTICISER, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SOLVENT

Neopentyl Glycol Dipelargonate is a sophisticated emollient and skin-conditioning agent, adept at smoothing and softening the skin's surface. It forms a protective, non-greasy barrier, enhancing moisture retention and imparting a luxurious, velvety feel to formulations.

Summary

Emollient Skin-Conditioning Agent Solvent Solubilizer Dispersing Agent Plasticizer

Science

Mechanism of Action

Operating primarily as an emollient, Neopentyl Glycol Dipelargonate conditions the skin by creating a lightweight, occlusive barrier that effectively seals in hydration, thus preventing transepidermal water loss and promoting a softer, more supple complexion. Its unique structure contributes to exceptional spreadability and a desirable silky, non-greasy texture in cosmetic applications. Beyond its skin benefits, it acts as a versatile solvent, facilitating the dissolution of other ingredients like UV filters and silicones, and functions as a dispersing agent for pigments, optimizing formulation homogeneity.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

This ingredient exhibits general compatibility with a wide range of cosmetic components, characterized by high spreadability and efficient absorption into the skin. While a specific optimal pH for Neopentyl Glycol Dipelargonate is not defined, a similar ester, Neopentyl Glycol Diethylhexanoate, maintains stability at a neutral pH. Its branched-chain structure allows for the dissolution of silicones, making it suitable for hot pours, gels, and various emulsion systems.

Synergies

  • UV filters (as a solubilizer)
  • Pigments (as a dispersing agent)
  • Silicones (as a solvent)

Safety

Safety Profile

CIR Status
Safe as used
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has deemed 'Neopentyl Glycol Dicaprylate/Dipelargonate/Dicaprate' safe for use in cosmetics as a group. A specific maximum concentration for Neopentyl Glycol Dipelargonate alone has not been explicitly reported to regulatory programs. However, a related ester, Neopentyl Glycol Diethylhexanoate, has been reported in concentrations up to 57% in face, neck, body, and hand products. It is generally not anticipated to cause skin irritation with prolonged or repeated application, and the potential for allergic reactions is considered low, although individuals with pre-existing sensitivities may react. Cosmetic ingredients do not typically require FDA approval prior to market entry in the U.S.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Neopentyl Glycol Dipelargonate is a valuable emollient and conditioning agent, universally compatible with all skin types, enhancing both skin feel and formulation aesthetics with low risk of irritation or comedogenicity.

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