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NEOPENTYL GLYCOL DICAPRATE.

Valuable CAS 27841-06-1 / SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

Neopentyl Glycol Dicaprate is a lightweight, non-greasy ester that functions as an exceptional emollient in skincare formulations. It significantly improves texture, enhances spreadability, and creates a breathable barrier on the skin, contributing to improved hydration and a soft, silky feel.

Summary

Emollient Skin Conditioning Stabilising Solvent Texture Enhancer

Science

Mechanism of Action

This 'fat-loving' emollient readily integrates into the skin's lipid layers, delivering a smooth, non-greasy sensory experience. It establishes a breathable film that minimizes transepidermal water loss, thereby boosting skin hydration and softness. Furthermore, its solvent properties aid in dispersing active ingredients, ensuring uniform distribution and optimizing their effectiveness within the formulation.

Research

Clinical Evidence

High confidence
Effective range 0.017–22.7%
Optimal

2-6%

Key findings

  1. 01 The Cosmetic Ingredient Review (CIR) Expert Panel deemed it safe, observing usage concentrations in surveyed products ranging from 0.017% to 22.7%.
  2. 02 Industry data suggests that concentrations between 2% and 6% typically provide optimal textural and performance benefits across most product types.
  3. 03 Higher concentrations, up to 10%, are well-tolerated in rinse-off formulations, enhancing sensory and delivery characteristics.
  4. 04 Maximum reported concentrations include up to 40% in specific leave-on formulations, such as lipsticks, and up to 50% in eye makeup removers.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH 3 – 8
0 7 14

Stability

Neopentyl Glycol Dicaprate demonstrates robust stability across a broad pH range of 3-8 and maintains integrity through various temperatures, from freezing to heat-activated processes. Its presence can enhance the overall stability and extend the shelf life of cosmetic formulations.

Safety

Safety Profile

CIR Status
Safe as used
Max tested
40%
Sensitization risk Low

Deemed safe by the Cosmetic Ingredient Review (CIR) Expert Panel, Neopentyl Glycol Dicaprate is generally considered non-toxic. Clinical studies indicate a low risk of allergic reactions or skin irritation. It is listed in the FDA Global Substance Registration System (GSRS). A preliminary patch test is recommended, particularly for individuals with hypersensitive skin.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Neopentyl Glycol Dicaprate is a valuable ingredient, prized for its ability to enhance sensory qualities, improve active ingredient dispersion, and provide effective, lightweight moisturization across all skin types with a low risk of irritation or comedogenicity.

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