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Moumoujus

NELUMBO NUCIFERA SEED EXTRACT.

Insufficient Data CAS 85085-51-4 / ANTIMICROBIAL, ANTIOXIDANT, ASTRINGENT, HAIR CONDITIONING, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SKIN PROTECTING

Nelumbo Nucifera Seed Extract is a multi-functional botanical ingredient derived from the lotus seed, offering comprehensive benefits for skin health. It is valued for its antioxidant, anti-aging, and skin brightening properties, while also contributing to hydration, sebum regulation, and a soothing effect.

Summary

antimicrobial antioxidant astringent emollient hair conditioning skin conditioning skin protecting sebum regulating anti-aging skin brightening anti-inflammatory hydrating

Science

Mechanism of Action

This extract functions as a potent antioxidant, primarily due to the presence of flavonoids, alkaloids, vitamin C, and glutathione, which collectively protect the skin from harmful free radicals and prevent structural damage. It exhibits anti-aging effects by inhibiting elastase, thereby reducing wrinkle formation, and through factors like methyltransferase. Skin brightening is achieved by inhibiting DOPA-oxidase and tyrosinase. Additionally, it possesses antimicrobial properties beneficial for skin clarity and product preservation, acts as an astringent via tannins to cleanse the skin, aids in sebum regulation, and forms a protective layer to maintain skin hydration. The extract also contributes anti-inflammatory and soothing benefits.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Achieved 57% DOPA-oxidase inhibition, indicating a significant skin-whitening effect.
  2. 02 Demonstrated 49% elastase inhibition, contributing to anti-wrinkle efficacy.
  3. 03 Exhibited potent free radical scavenging with an IC50 value.
  4. 04 Showed DPPH radical scavenging activity ranging from 58.42% to 89.15%, with higher activity at increased concentrations.
  5. 05 Included in topical formulas to combat aging, leveraging its anti-aging factors and antioxidant content.

Transparency

Dusting Analysis

Not commonly dusted

No information regarding 'dusting' or ineffective percentages was found in the provided research data.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

A related Nelumbo nucifera extract (not explicitly seed) showed stability in a water cream formulation at 4% concentration for 30 days across various temperature conditions.

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) Expert Panel has issued a Tentative Report as of March 2025, indicating insufficient data to determine the safety of Nelumbo nucifera-derived ingredients, including Nelumbo Nucifera Seed Extract, under intended cosmetic use conditions. While Nelumbo Nucifera Seed Extract is listed in the FDA Voluntary Cosmetic Registration Program (VCRP) database, safety conclusions are pending. It is important to distinguish this from Nelumbo Nucifera Flower Extract, which is generally considered non-toxic and well-tolerated with low irritation potential (Primary Cutaneous Irritation Index of 0.20).

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

While Nelumbo Nucifera Seed Extract demonstrates promising multi-functional benefits for skin health, including antioxidant, anti-aging, and brightening effects, further comprehensive safety data is required by the CIR Expert Panel for a definitive safety determination.

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References

Sources