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Moumoujus

NELUMBO NUCIFERA MERISTEM CELL CULTURE CONDITIONED MEDIA.

Insufficient Data / HUMECTANT

Nelumbo Nucifera Meristem Cell Culture Conditioned Media is an advanced ingredient derived from the cultured stem cells of the lotus plant. This biomimetic extract is rich in natural biochemicals such as flavonoids, alkaloids, and growth factors. It aims to revitalize the skin by promoting hydration, offering soothing benefits, and targeting multiple signs of aging through its potent cellular support.

Summary

Humectant Antioxidant Soothing Skin Conditioning Anti-inflammatory Anti-aging Skin Brightening Collagen Boosting Cell Regenerative Hydrating

Science

Mechanism of Action

This ingredient acts through a sophisticated blend of active compounds, including triterpenoids, flavonoids, alkaloids, and polyphenols, complemented by growth factors, cytokines, and chemokines inherent to conditioned media. These components collectively deliver antioxidant and anti-inflammatory effects. Specific alkaloid constituents are suggested to inhibit tyrosinase, aiding in melanogenesis reduction for enhanced skin brightening. Furthermore, insights from Nelumbo nucifera germ extract indicate its capacity to stimulate collagen production, foster cell proliferation, and rejuvenate aging fibroblasts by facilitating the removal of abnormal proteins via autophagy, thereby supporting comprehensive tissue repair and renewal.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel, in a Draft Tentative Report issued March 2025, concluded that current data are insufficient to make a definitive safety determination for Nelumbo Nucifera Meristem Cell Culture Conditioned Media and 13 other Nelumbo nucifera-derived ingredients. Further toxicological data are necessary. Despite this, some Nelumbo Nucifera ingredients are listed within the FDA Voluntary Cosmetic Registration Program (VCRP) database, and it is assessed with low irritancy.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Insufficient Data

While offering promising benefits for skin rejuvenation, hydration, and brightening, a conclusive safety assessment by the CIR Expert Panel is pending due to insufficient data.

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