Science
Mechanism of Action
This extract operates by leveraging its phenolic constituents, which actively scavenge free radicals, thereby inhibiting lipid peroxidation and preventing oxidative stress. This mechanism helps to maintain the integrity of skin cells and fortify the skin's natural defenses, promoting overall skin health.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
No specific regulatory status (CIR, SCCS, FDA) has been established for NAUCLEA ORIENTALIS CALLUS EXTRACT in cosmetic applications. However, acute and subchronic oral toxicity studies on Nauclea orientalis bark extract in Wistar rats, at a dose of 2.0 g/kg, showed no signs of mortality or conspicuous toxicity over 14-30 days, suggesting a generally low oral toxicity profile for the plant material. Specific topical safety data for the callus extract is not available.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Further research, particularly on topical clinical efficacy and specific safety assessments for the callus extract, is needed to fully establish its precise role and optimal application in skincare formulations.
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References
Sources