Science
Mechanism of Action
Natto Gum primarily functions as a film-forming humectant, establishing a delicate yet robust barrier on the skin's surface. This barrier actively reduces transepidermal water loss (TEWL) and provides essential protection against environmental stressors. Its rich composition of polysaccharides and potent Polyglutamic Acid (PGA) enables significant water-binding capabilities, leading to intense hydration of the skin. The ingredient also supports the skin’s natural hydration network by boosting natural moisturizing factors (NMFs) and augmenting the effectiveness of intrinsic hyaluronic acid, thereby fortifying the skin’s structural integrity. Additionally, Natto Gum exhibits antioxidant activity, counteracting free radical damage, promoting skin soothing, supporting healthy cell regeneration, and potentially contributing to a brighter complexion and the reduction of fine lines.
Research
Clinical Evidence
High confidence5%
Key findings
- 01 Demonstrably captures and retains moisture, significantly improving skin moisture content and elasticity, while reducing transepidermal water loss (TEWL). This effect is particularly noted for larger molecular weight Natto Gum variants (e.g., AquaMAX HM).
- 02 More effectively inhibits hyaluronidase activity, which helps to preserve and increase the skin’s natural hyaluronic acid content. It also elevates levels of natural moisturizing factors (NMFs) and enhances overall epidermal structural integrity, especially with smaller molecular weight Natto Gum variants (e.g., AquaMAX LM).
- 03 Highly effective in delivering profound moisture to the deeper layers of the skin, surpassing the moisturizing efficacy of hyaluronic acid in some studies, and also contributes to gentle skin brightening.
- 04 Consistently provides excellent moisturizing and lubricating benefits to the skin.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Natto Gum is readily soluble in water, glycols, and ethanol, and can be efficiently dispersed within various cream or gel formulations. It exhibits stability across a pH range of 4-7, with an optimal pH for formulation typically cited between 5.5-6.5 or 6.0-7.0. It is crucial to avoid processing temperatures above 40°C during mixing to maintain its integrity. For long-term stability, the ingredient should be stored in a cool, dry, and light-protected environment. As a weak electrolyte, formulators should carefully consider its compatibility with certain thickeners or gelling agents, as incompatibility may lead to formula destabilization.
Conflicts
- High-pH ingredients
- Strong exfoliants
- Thickeners/gel makers intolerant to electrolytes
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has thoroughly assessed Natto Gum, along with other microbial polysaccharide gums, concluding its safety for use in cosmetic formulations under current industry practices and concentrations. The U.S. Food and Drug Administration (FDA) also recognizes Natto Gum as a safe cosmetic ingredient. Adverse reactions are uncommon, though a preliminary patch test is always prudent before widespread application. Studies generally indicate that it is well-tolerated, with unsuitability primarily confined to individuals with known specific soy allergies.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Natto Gum is a valuable ingredient for sophisticated skincare formulations, providing superior, multi-faceted hydration, robust barrier protection, and supporting overall skin health with a highly favorable safety and compatibility profile.
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References
Sources