Science
Mechanism of Action
This botanical extract functions primarily through its robust antioxidant capacity, effectively neutralizing free radicals to shield skin from oxidative stress induced by environmental pollutants and blue light, thereby mitigating signs of premature aging. It also demonstrates anti-sebum activity, which helps regulate and reduce excessive oil production, promoting a matte finish and minimizing pore congestion. Furthermore, the extract exhibits soothing and anti-inflammatory effects, capable of calming sensitive or irritated skin and reducing redness. Its antimicrobial properties contribute to reducing skin infections, including those associated with acne, while also serving as a skin tonic to invigorate and enhance overall skin radiance and vitality. The extract is rich in beneficial compounds, including vitamins (A, B1, B2, C, E, PP), minerals (iodine, iron, calcium, phosphorus), phenolic compounds, and flavonoids.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 At concentrations between 10-500 µg/mL, the extract dose-dependently reduced thiobarbituric acid reactive substances (TBARS) formation, indicating significant lipid peroxidation inhibition. It also demonstrated chelating activity for Fe2+ ions, suggesting a protective effect against oxidative damage.
- 02 An ethanolic extract showed moderate reducing power in a DPPH radical scavenging test, with an IC50 value of approximately 105-109 µg/ml for hydroalcoholic extracts. A concentration of 100 mg/ml (ethanolic extract) increased reducing power to 60.38%.
- 03 In an irritant contact dermatitis model, topical application of the extract demonstrated anti-inflammatory activity. It significantly reduced ear edema, inflammatory cell infiltration, and levels of inflammatory cytokines, operating via glucocorticoid receptor-dependent and NF-κB pathways. Specific human topical concentrations were not provided.
Transparency
Dusting Analysis
Insufficient data available to determine dusting parameters for this extract.
The Formula
Formulation
Safety
Safety Profile
Generally recognized as safe for topical cosmetic use, being a natural and non-toxic ingredient well-tolerated across all skin types, with adverse reactions being uncommon. EWG Skin Deep rates it with 'LOW' concern across various health categories, including cancer and immunotoxicity. A patch test is always recommended prior to broad application. Data regarding safe topical usage during pregnancy and breastfeeding is limited; therefore, consultation with a healthcare professional is advised for individuals in these categories.
Your Skin
Skin Compatibility
Our Assessment
Verdict
NASTURTIUM OFFICINALE FLOWER/LEAF EXTRACT is a valuable ingredient, offering comprehensive benefits from antioxidant protection and anti-inflammatory action to sebum regulation and skin conditioning, suitable for virtually all skin types.
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