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Moumoujus

NANNOCHLOROPSIS GADITANA.

Valuable / ANTIOXIDANT, SKIN CONDITIONING

Nannochloropsis gaditana is a potent microalgae extract rich in antioxidants and skin-conditioning compounds. It offers multifaceted skin protection, enhancing cellular vitality, combating oxidative stress, and addressing signs of aging and hyperpigmentation.

Summary

antioxidant skin-conditioning anti-aging anti-inflammatory brightening hydrating UV protection (potential)

Science

Mechanism of Action

This microalgal extract delivers its benefits primarily through antioxidant action, safeguarding skin from free radical damage and oxidative stress. It functions as a skin conditioning agent, bolstering the skin's natural barrier to promote softness and hydration. Molecularly, it positively influences genes critical for skin texture and hydration (e.g., AQP3, Col6A1, FBN1) while modulating those linked to irritation, DNA damage, and aging (e.g., IL1R, PCNA, FOXO3). Its anti-aging and brightening effects are partly attributed to the inhibition of elastase and tyrosinase enzymatic activities, and it may also provide UV protective benefits.

Research

Clinical Evidence

High confidence
Effective range 408 µg/ml–1000 µg/mL%
Optimal

N/A

Key findings

  1. 01 Significantly increased ATP levels, indicating enhanced cell viability in human dermal fibroblasts, suggesting robust skin protection against oxidative stress.
  2. 02 Demonstrated inhibition of human elastase activity, contributing to anti-wrinkle efficacy.
  3. 03 Exhibited inhibition of tyrosinase activity, indicating potential for reducing hyperpigmentation.
  4. 04 Showed broad skin protective functions including anti-melanogenic, antioxidant, skin-moisturizing, anti-inflammatory, anti-wrinkling, and UV protective effects, with low cytotoxicity. Specifically decreased mushroom tyrosinase activity by up to 59.2%.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Nannochloropsis gaditana is rich in polar lipids, essential fatty acids, and antioxidants. While the stability of its biomass's polyunsaturated fatty acids and pigments can be maintained under specific storage conditions (e.g., 4°C, nitrogen or air atmosphere), specific optimal pH ranges for cosmetic formulation stability are not yet established. Encapsulation may be a viable strategy to enhance stability and bioavailability within cosmetic products.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Nannochloropsis gaditana extract is generally considered safe for topical use, demonstrating no irritation in a 3D human skin model and a low comedogenicity rating of 1. While side effects are rare, a patch test is recommended prior to widespread application. Notably, the FDA approved Nannochloropsis algae as a novel food, and safety evaluations of its oil identified a no-observed-adverse-effect level (NOAEL) of 2.8 g/kg BW in oral subchronic toxicity and teratogenicity studies.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Nannochloropsis gaditana is a valuable ingredient, offering comprehensive skin protection from oxidative stress to visible signs of aging and hyperpigmentation, with excellent compatibility across all skin types.

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