Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle

MYRTRIMONIUM BROMIDE.

Valuable CAS 1119-97-7 / PRESERVATIVE

Myrtrimonium Bromide is a cationic surfactant and quaternary ammonium salt, primarily valued for its robust antimicrobial and preservative capabilities in skincare and cosmetic formulations. It actively inhibits the proliferation of diverse microorganisms, thereby extending product shelf-life and supporting skin hygiene.

preservative antistatic antimicrobial antiseptic conditioning

Science

This ingredient functions as a cationic surfactant, disrupting microbial cellular integrity. Its mechanism involves interaction with bacterial Toll-like receptors, alteration of mitochondrial membrane potential, and inhibition of H+ ATP synthase, leading to membrane depolarization and caspase activation. This cascade effectively eliminates bacterial cells, contributing significantly to the microbiological stability of cosmetic products.


Research

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Exhibits antibacterial efficacy against both wild-type and benzalkonium chloride-resistant strains of Staphylococcus aureus, acting as an antiseptic agent.

Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 6 – 8
0 7 14

Stability

A 1% aqueous solution demonstrates a stable pH range of 6.0 to 8.0, indicating optimal stability within these parameters.


Safety

CIR Status
Safe with restrictions
Max tested
0.1%
Sensitization risk Moderate

The Cosmetic Ingredient Review (CIR) deemed similar quaternary ammonium compounds safe in rinse-off products and up to 0.25% in leave-on applications. However, the EU's Scientific Committee on Consumer Safety (SCCS) permits Myrtrimonium Bromide as a preservative at a maximum concentration of 0.1%. Use at higher concentrations for non-preservative functions necessitates additional safety data. While generally considered safe within appropriate limits, individuals may experience skin irritation, redness, itching, or allergic reactions, making patch testing advisable. Formulators should also consider potential combination effects, as quaternary ammonium compounds are known irritants at elevated levels.


Your Skin

Yes Normal
No Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

Myrtrimonium Bromide is a valuable ingredient, primarily for its effective broad-spectrum antimicrobial action and preservative qualities, which are essential for product stability and targeted skin applications, provided its use adheres to established concentration guidelines.


Related

Finding similar ingredients…