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MYRISTOYL TRIPEPTIDE-31.

Valuable / SKIN CONDITIONING

Myristoyl Tripeptide-31 is a sophisticated biomimetic signal lipopeptide engineered to modulate specific gene expressions crucial for cell renewal and epidermal differentiation. It adeptly supports skin homeostasis, offering comprehensive anti-aging benefits comparable to retinoids but without the typical associated side effects.

Skin Conditioning Anti-aging Anti-wrinkle Collagen Boosting Skin Elasticity Enhancer Skin Firming Brightening Photoprotection Pore Refining Cell Renewal Modulation

Science

This lipopeptide functions by modulating gene expression related to cellular turnover and epidermal differentiation, thereby stabilizing skin's natural balance. It mimics retinoid actions by inhibiting the transcription and translation of MMP-1, an enzyme responsible for collagen degradation, while simultaneously boosting Type I procollagen production. This dual action strengthens skin structure, perceptibly reduces pore volume, and enhances overall elasticity and firmness. Furthermore, it fortifies the skin's intrinsic defenses against environmental aggressors, including UV radiation.


Research

Medium confidence
Effective range N/A
Optimal

0.1%

Key findings

  1. 01 Clinical investigation at 0.1% demonstrated efficacy in ameliorating photoaging indicators such as wrinkles and mottled hyperpigmentation. The ingredient was observed to elevate collagen synthesis and normalize skin resilience against environmental stressors like UV irradiation, all without adverse effects, positioning it as a well-tolerated substitute for retinols and retinoids.

Transparency

Not commonly dusted

The Formula

Solubility
Both
Optimal pH N/A
0 7 14

Stability

The raw material is a stable, pH-neutral white powder. For optimal stability, it should be stored in a cool, dry place between 2-8°C, protected from light. Long-term storage is recommended at -20°C to -15°C.


Safety

CIR Status
Not reviewed
Max tested
0.1%
Sensitization risk Low

This ingredient is documented as non-irritating for both skin and eyes, and is verified to be free from heavy metals. Its profile as a retinoid alternative without the typical side effects makes it particularly appealing for sensitive skin types.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Valuable

Myristoyl Tripeptide-31 is a valuable, well-tolerated biomimetic lipopeptide, delivering significant anti-aging results, including enhanced collagen production and visible reduction of wrinkles and hyperpigmentation, offering a sophisticated alternative to traditional retinoids.


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