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MYRISTOYL TETRAPEPTIDE-4.

Valuable CAS - / SKIN CONDITIONING

Myristoyl Tetrapeptide-4 is a sophisticated signaling peptide that actively communicates with skin and hair cells to stimulate the synthesis of crucial structural proteins. It is recognized for its capacity to enhance hair strength and growth, while simultaneously boosting skin's firmness, elasticity, and endogenous repair processes.

Skin conditioning Hair conditioning Anti-aging Moisturizer Anti-wrinkle Supports extracellular matrix Promotes wound healing Skin repair

Science

Functioning as a signaling peptide, Myristoyl Tetrapeptide-4 orchestrates specific biological responses within cells. It stimulates the expression of keratin genes, leading to increased keratin synthesis that strengthens hair follicles and promotes the growth of thicker, longer hair strands. In the skin, it activates the development of dermal papilla cells and signals skin cells to boost the production of collagen and fibronectin, which are vital for maintaining skin’s firmness, elasticity, and smooth texture, thus diminishing the appearance of fine lines and wrinkles. Furthermore, it supports the extracellular matrix and facilitates wound healing and skin repair.


Research

Medium confidence
Effective range N/A
Optimal

0.05%


Transparency

Not commonly dusted

Insufficient data to determine dusting potential.


The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Stock solutions should be precisely aliquoted and stored at -80°C for up to 6 months or -20°C for 1 month in sealed containers, away from moisture, to prevent inactivation from repeated freeze-thaw cycles.


Safety

CIR Status
Safe as used
Max tested
0.05%
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) Expert Panel concluded that Myristoyl Pentapeptide-4 (often synonymous with Myristoyl Tetrapeptide-4), along with other related pentapeptides, is safe for use in cosmetics. While some sources continue to cite a 0.05% concentration for various applications, the CIR clarified that a previously reported 0.05% for Myristoyl Pentapeptide-4 was for an experimental product. Corrected maximum reported concentrations for *related* pentapeptides include 0.0035% in hair conditioners and 0.012% in face and neck preparations, underscoring the importance of formulation-specific concentration limits.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

Myristoyl Tetrapeptide-4 is a valuable signaling peptide that actively supports skin regeneration, firmness, and elasticity, while also promoting stronger, denser hair growth, and is considered safe for cosmetic applications.


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