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Moumoujus

MYRISTOYL TETRAPEPTIDE-34.

Valuable / SKIN CONDITIONING

Myristoyl Tetrapeptide-34 is a potent anti-aging tetrapeptide engineered to precisely target and inhibit key matrix-degrading enzymes, specifically MMP-1. This action is crucial for preserving and restoring skin's collagen integrity, leading to improved elasticity and overall skin health.

Summary

Anti-aging Collagen Support Elasticity Improvement Anti-inflammatory Redness Reduction Hydration Boosting Skin Barrier Reinforcement

Science

Mechanism of Action

This synthetic tetrapeptide operates by effectively inhibiting Matrix Metalloproteinases (MMPs), particularly MMP-1, which are enzymes responsible for collagen degradation. By doing so, it facilitates the recovery of collagen levels and mitigates MMP production induced by oxidative stress from Reactive Oxygen Species (ROS) and Reactive Nitrogen Species (RNS). Beyond collagen protection, it also stimulates new collagen synthesis, enhances skin's intrinsic elasticity, reduces inflammation and associated redness, optimizes hydration levels, and fortifies the skin barrier function.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 In vitro investigations utilizing small concentrations demonstrated a significant reduction in the expression of genes and subsequent production of MMP-1 under both UV-stimulated and non-stimulated conditions. This activity led to a noticeable recovery of collagen levels. Additionally, it considerably lowered MMP levels that were produced due to the influence of Reactive Oxygen Species (ROS) or Reactive Nitrogen Species (RNS.
  2. 02 Supplier-conducted in vivo clinical studies, though specific details on concentration and methodology are not provided, indicate that this peptide is among the most promising anti-aging ingredients currently available.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Unknown
Optimal pH N/A
0 7 14

Stability

The raw ingredient, a white or off-white powder, is described as highly stable for maximal performance across diverse formulations. The pH of the raw material itself is indicated as neutral. For optimal preservation, the powder should be stored in a cool, dry, and light-protected environment at 2-8°C, with long-term storage at -20°C to -15°C in an airtight package recommended.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Myristoyl Tetrapeptide-34 is a synthetic cosmetic peptide. Supplier information reports it to be free from heavy metals and without skin or eye irritation potential. Specific safety assessments by regulatory bodies such as the CIR or SCCS for Myristoyl Tetrapeptide-34 were not identified; related CIR reports pertain to Myristoyl Pentapeptide-4, a distinct peptide.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Myristoyl Tetrapeptide-34 is a valuable peptide for advanced skincare formulations, effectively combating signs of aging by protecting collagen from degradation and enhancing overall skin resilience and health.

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