Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle
Moumoujus

MYRISTOYL SUCCINOYL ATELOCOLLAGEN.

Valuable / SKIN CONDITIONING

Myristoyl Succinoyl Atelocollagen is a sophisticated derivative of atelocollagen, a vital skin protein, engineered to enhance skin's youthful appearance and resilience. This modified form delivers targeted benefits by improving hydration, supporting the skin barrier, and visibly reducing signs of aging.

Summary

Skin Conditioning Moisturizer Anti-aging Barrier Support

Science

Mechanism of Action

As a modified atelocollagen, this ingredient works by leveraging collagen's inherent role as a structural scaffold in the skin, which naturally degrades with age. Its succinylated component is a potent humectant, drawing and binding water molecules to create a 'bulking effect' that can visibly diminish periorbital wrinkles. Furthermore, it actively suppresses transepidermal water loss (TEWL), thereby strengthening the skin's barrier function. The myristoyl modification is strategically incorporated to boost its affinity with the skin's lipid barrier, potentially facilitating absorption and enhancing overall skin compatibility.

Research

Clinical Evidence

Medium confidence
Effective range 0.4–0.8%
Optimal

0.4%

Key findings

  1. 01 Topical application of 0.4% succinylated atelocollagen for two months demonstrated statistically significant improvements in periorbital wrinkles. Additionally, increases in epidermal thickness and collagen fibers were observed, though not always statistically significant across all groups.
  2. 02 Formulations containing 0.8% Myristoyl Succinoyl Atelocollagen (within a Shark Fin Atelocollagen MS product) were shown to suppress transepidermal water loss (TEWL) and enhance skin barrier function, leading to more apparent recovery from chapping.

Transparency

Dusting Analysis

Commonly dusted
Min. effective
0.4%
Red flag below
0.005%

The Cosmetic Ingredient Review (CIR) Expert Panel's maximum reported leave-on concentration for the broader Atelocollagen category is 0.005%. However, clinical studies demonstrating efficacy for Myristoyl Succinoyl Atelocollagen in wrinkle reduction and barrier improvement utilized significantly higher concentrations, specifically 0.4% and 0.8%. This discrepancy indicates that the ingredient may frequently be included in formulations at levels below its clinically effective threshold.

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Atelocollagen is inherently hydrophilic with strong moisture-retaining properties. The myristoyl succinoyl modification significantly enhances its formulation versatility, improving compatibility with both aqueous and certain lipophilic components. This dual solubility is supported by emulsion stability tests showing integration with PEG 400 and olive oil. Specialized technology can be employed to combine it with other lipophilic and moisturizing ingredients.

Safety

Safety Profile

CIR Status
Safe as used
Max tested
0.005%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel concluded that Atelocollagen, the broader category encompassing this ingredient, is safe for use in cosmetics under current practices and concentrations. The maximum reported leave-on concentration for Atelocollagen is 0.005%. No specific SCCS or FDA safety status directly for MYRISTOYL SUCCINOYL ATELOCOLLAGEN has been identified.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Myristoyl Succinoyl Atelocollagen is a valuable ingredient, clinically proven to deliver anti-aging benefits by reducing wrinkles and improving skin barrier function, particularly suitable for hydrating and supporting dry and sensitive skin types.

Related

Similar Ingredients

Finding similar ingredients…