Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle
Moumoujus

MYRISTOYL PENTAPEPTIDE-17.

Valuable CAS 959610-30-1 / SKIN CONDITIONING

Myristoyl Pentapeptide-17 is a synthetic pentapeptide specifically designed to stimulate keratin synthesis, leading to enhanced growth, density, and strength of eyelashes, eyebrows, and hair. Beyond its significant impact on hair follicles, it also offers benefits for skin vitality, including anti-aging, anti-inflammatory, and antibacterial actions.

Summary

Eyelash care Hair growth stimulation Keratin synthesis promotion Anti-aging Anti-inflammatory Antibacterial Skin smoothing Barrier enhancement Cell regeneration

Science

Mechanism of Action

This advanced synthetic peptide functions by directly activating keratin genes within hair papilla cells, thereby significantly augmenting the production of keratin, the fundamental structural protein of hair. This process not only promotes thicker and more resilient hair but also extends the hair's natural growth phase and optimizes nutrient delivery to the follicles. Additionally, Myristoyl Pentapeptide-17 supports broader skin health by stimulating cell regeneration, refining skin texture, mitigating pro-inflammatory cytokines, and exhibiting antimicrobial efficacy against common skin pathogens like C. acnes and yeast, bolstering the skin's inherent immune defense and barrier function.

Research

Clinical Evidence

High confidence
Effective range 0.01–10%
Optimal

3%

Key findings

  1. 01 In a care solution, continuous use resulted in a 23% increase in eyelash length and density after two weeks, progressing to a 71% improvement by six weeks.
  2. 02 Within a complex formulation alongside other peptides, this ingredient notably activated eyelash follicle keratin genes, stimulated keratin-5 production, and enhanced nutrient absorption, leading to improvements in eyelash count, luster, thickness, and length.
  3. 03 An open-label study over 90 days of nightly application showed significant gains in eyelash length (10.52%), volume (9.3%), luster (11.43%), thickness (35%), and curl (50.83%) in healthy female subjects.

Transparency

Dusting Analysis

Not commonly dusted
Min. effective
0.01%
Red flag below
0.005%

While a general suggested usage range begins at 0.01%, achieving pronounced effects, particularly for eyelash growth, often necessitates concentrations within the 3-10% range. Formulations below 0.01% may not deliver clinically meaningful results, potentially constituting a 'dusting' application.

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Exhibits robust stability across a wide spectrum of pH levels and various packaging formats. For optimal integration and stability, it should be incorporated into the low-temperature water phase of a formulation. Storage should avoid excessive heat and incompatible materials. Its typically colorless to light beige, odorless solution ensures minimal impact on product aesthetics.

Safety

Safety Profile

CIR Status
Safe as used
Sensitization risk Low

Myristoyl Pentapeptide-17 is recognized for its high safety profile, making it suitable for delicate skin areas, including the eyelids, with no significant adverse reactions reported. It is dermatologically tested, confirmed to be gentle, and widely approved as a cosmetic ingredient. Comprehensive safety assessments for related pentapeptides by the CIR Expert Panel, indicating safety at concentrations up to 0.01%, support its low potential for skin or eye irritation and sensitization.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Myristoyl Pentapeptide-17 is a valuable peptide, clinically substantiated for its significant ability to enhance eyelash and hair growth through keratin stimulation, while also offering beneficial anti-aging, anti-inflammatory, and skin barrier-supporting properties with an excellent safety profile.

Related

Similar Ingredients

Finding similar ingredients…