Science
Mechanism of Action
This advanced pseudoceramide functions by integrating into the skin's Multi-Lamellar Emulsion (MLE) system, precisely mirroring the natural organization of lipids within healthy human skin. This process actively restores compromised barrier function, rebalancing the skin's natural lipid structure to enhance water retention and create a robust shield against irritants and allergens. It also contributes to skin and hair conditioning.
Research
Clinical Evidence
High confidenceN/A
Key findings
- 01 As a key component of Multi-Lamellar Emulsion (MLE) technology, MYRISTOYL/PALMITOYL OXOSTEARAMIDE/ARACHAMIDE MEA effectively restores healthy barrier function and mitigates chronic conditions such as atopic dermatitis by rebalancing the skin's natural lipid structure, ensuring proper ratios and lamellar patterns.
- 02 Co-application of an MLE (containing MYRISTOYL/PALMITOYL OXOSTEARAMIDE/ARACHAMIDE MEA as PC-9S) with 1.0% hydrocortisone significantly reduced impairment in epidermal permeability barrier function, maintained skin hydration and surface pH, and minimized damage to stratum corneum integrity, thereby alleviating skin atrophy caused by topical hydrocortisone.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
This ingredient, functioning optimally within Multi-Lamellar Emulsion (MLE) technology, demonstrates stability and efficacy within an acidic to slightly acidic pH range of 4.5 to 6.0. This range is conducive to maintaining the skin's natural acidic mantle, typically between pH 4.5 and 5.5.
Synergies
- Other physiological lipids within Multi-Lamellar Emulsion (MLE) systems for enhanced barrier reconstruction.
Safety
Safety Profile
EWG Skin Deep assigns this ingredient a 'LOW' concern rating across categories including cancer, allergies & immunotoxicity, and developmental and reproductive toxicity. It is not listed on EWG's Restricted or Unacceptable Lists. The Good Scents Company has identified no GHS classifications, hazard statements, or precautionary statements.
Your Skin
Skin Compatibility
Our Assessment
Verdict
MYRISTOYL/PALMITOYL OXOSTEARAMIDE/ARACHAMIDE MEA is a valuable pseudoceramide, adept at restoring the skin's essential barrier function, rebalancing lipid structure, and mitigating chronic skin conditions.
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